Evidence map›Paper›PMID 23974176›Full record

ReviewOrganogenesis

Mechanisms of respiratory innervation during embryonic development.

Linh Aven, Xingbin Ai

Open access · hybridAbstract readReview
In one paragraph

Review in Organogenesis. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 1 pooled it
1.2field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 1 synthesis or guideline pooled it, 44 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Mapping Embryonic Mouse Lung Development Using Enhanced Spatial Transcriptomics.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Article
  4. Neuroplasticity and neuroimmune interactions with type 2 inflammation in asthma.European respiratory review : an official journal of the European Respiratory Society · 2026
    Review
  5. βNature communications · 2025
    Article
  6. Article
  7. Review
  8. Article
  9. Review
  10. Review
  11. Article
  12. SOX2 and SOX21 in Lung Epithelial Differentiation and Repair.International journal of molecular sciences · 2022
    Review
  13. Innervation in organogenesis.Current topics in developmental biology · 2022
    Article
  14. Identification of lung innervating sensory neurons and their target specificity.American journal of physiology. Lung cellular and molecular physiology · 2022
    Article
  15. Article
  16. Article
  17. Airway Innervation and Plasticity in Asthma.Physiology (Bethesda, Md.) · 2019
    Review
  18. Article
  19. Mechanisms of organophosphorus pesticide toxicity in the context of airway hyperreactivity and asthma.American journal of physiology. Lung cellular and molecular physiology · 2018
    Review
  20. Neurotrophins in Asthma.Current allergy and asthma reports · 2018
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Linh AvenThe Pulmonary Center; Boston University School of Medicine; Boston, MA USA.
Xingbin Ai
Boston University · USUniversity School · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

During embryogenesis, the development of the respiratory tract is closely associated with the formation of an extensive neuronal network. While the topic of respiratory innervation is not new, and similar articles were published previously, recent studies using animal models and genetic tools are breathing new life into the field. In this review, we focus on signaling mechanisms that underlie innervation of the embryonic respiratory tract.

Indexed as

Embryonic DevelopmentRespiratory SystemSignal TransductionAnimalsBrain-Derived Neurotrophic FactorHumansMiceNerve Growth FactorsNeuronsRatsBrain-Derived Neurotrophic FactorNerve Growth Factorsbrain-derived neurotrophic factorextrinsic neuronglial cell-derived neurotrophic factorintrinsic neuronlung developmentneurotrophinrespiratory tract

Identifiers

PMID23974176
PMCPMC3896590
OpenAlexW2014177624

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.