Evidence map›Paper›PMID 23973732›Full record

ArticleTheoretical population biology2013

Separation of the largest eigenvalues in eigenanalysis of genotype data from discrete subpopulations.

Katarzyna Bryc, Wlodek Bryc, Jack W Silverstein

Abstract read
In one paragraph

Article in Theoretical population biology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. A Genomic Reference Panel forG3 (Bethesda, Md.) · 2018
    Article
  8. Article
  9. Article
  10. Article
  11. Limitations of GCTA as a solution to the missing heritability problem.Proceedings of the National Academy of Sciences of the United States of America · 2016
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Katarzyna BrycDepartment of Genetics, Harvard Medical School, Boston, MA 02115, USA. Electronic address: kasia1@gmail.com.
Wlodek Bryc
Jack W Silverstein

Funding

Insights from ancient and recent population mixture relevant to medical geneticsF32HG006411 · NHGRI · HARVARD MEDICAL SCHOOL · PI BRYC, KATARZYNA · 2011 to 2013
$98k
NHGRI NIH HHS 5F32HG006411NHGRI NIH HHS F32 HG006411
6 · The paper itself

Abstract

We present a mathematical model, and the corresponding mathematical analysis, that justifies and quantifies the use of principal component analysis of biallelic genetic marker data for a set of individuals to detect the number of subpopulations represented in the data. We indicate that the power of the technique relies more on the number of individuals genotyped than on the number of markers.

Indexed as

Genetics, PopulationGenotypeHumansModels, TheoreticalEigenanalysisEigenvaluesNumber of subpopulationsPopulation structurePrincipal components analysis

Identifiers

PMID23973732
PMCPMC3825268

What OpenQuestion holds

Textmetadata
LicenceTDM
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.