Evidence map›Paper›PMID 23973089›Full record

ArticleJournal of electrocardiology

Catastrophic neurologic syndrome with dramatic ECG changes.

Zachary D Goldberger, Claire J Creutzfeldt, Ary L Goldberger

Abstract readCase Reports
In one paragraph

Article in Journal of electrocardiology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Zachary D GoldbergerUniversity of Washington School of Medicine, Harborview Medical Center, Seattle 98104, WA; Department of Internal Medicine, Division of Cardiology, Seattle 98104, WA.
Claire J CreutzfeldtUniversity of Washington School of Medicine, Harborview Medical Center, Seattle 98104, WA; Department of Neurology, Seattle 98104, WA.
Ary L GoldbergerDivision of Interdisciplinary Medicine and Biotechnology, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston 02215, MA. Electronic address: zgoldber@uw.edu.
Harborview Medical Center · USHarvard University · US

Funding

Research Resource for Complex Physiologic SignalsR01GM104987 · NIGMS · BETH ISRAEL DEACONESS MEDICAL CENTER · PI GOLDBERGER, ARY LOUIS, MARK, ROGER GREENWOOD · 2012 to 2019
$5.8M
NIGMS NIH HHS R01 GM104987NIGMS NIH HHS R01-GM104987
6 · The paper itself

Abstract

Cerebrogenic ECG abnormalities, especially prominent T wave inversions and prolongation of the QT(U) interval, are well-described. Brady- and tachyarrhythmias, including polymorphic VT, have been also described in the setting of neurologic injury. We report an unusual case of a 22-year-old man who presented with idiopathic acute encephalopathy. His hospital course was complicated by persistent fevers, along with refractory seizures treated with propofol. Serial ECG findings included marked ventricular repolarization prolongation with bursts of torsade de pointes, diffuse ST elevations simulating extensive myocardial ischemia or infarction, as well as a Brugada-like pattern. To our knowledge, this case is the first reported with the combination of such findings in a patient with a catastrophic neurologic syndrome.

Indexed as

Brugada SyndromeCatastrophic IllnessConfusionDiagnosis, DifferentialElectrocardiographyHumansMaleSeizuresSyndromeYoung AdultBrugada patternElectrocardiogramPolymorphic ventricular tachycardiaPropofol toxicityPseudo-infarct patternQT prolongationTorsade de pointes

Identifiers

PMID23973089
PMCPMC4104694
OpenAlexW2036737156

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.