Evidence map›Paper›PMID 23972420›Full record

ArticleJournal of psychosomatic research2013

General anxiety symptoms after acute lung injury: predictors and correlates.

Jennifer E Stevenson, Elizabeth Colantuoni, O Joseph Bienvenu, Thiti Sricharoenchai, Amy Wozniak, Carl Shanholtz, Pedro A Mendez-Tellez, Dale M Needham

Open access · greenAbstract readMulticenter Study
In one paragraph

Article in Journal of psychosomatic research, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
3.8field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 41 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Jennifer E StevensonDepartment of Physical Medicine and Rehabilitation, the Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Elizabeth Colantuoni
O Joseph Bienvenu
Thiti Sricharoenchai
Amy Wozniak
Carl Shanholtz
Pedro A Mendez-Tellez
Dale M Needham
Johns Hopkins University · USJohns Hopkins Medicine · USUniversity of Maryland, Baltimore · US

Funding

VENTILATOR ASSOCIATED LUNG INJURY: MOLECULAR APPROACHESP50HL073994 · NHLBI · JOHNS HOPKINS UNIVERSITY · PI BROWER, ROY G. · 2003 to 2007
$21.3M
Institute for Clinical and Translational ResearchUL1TR000424 · NCATS · JOHNS HOPKINS UNIVERSITY · PI FORD, DANIEL ERNEST · 2012 to 2012
$6.0M
NCATS NIH HHS UL1 TR000424NCATS NIH HHS UL1 TR 000424-06NHLBI NIH HHS P050 HL 73994NHLBI NIH HHS P50 HL073994
6 · The paper itself

Abstract

objectiveAcute lung injury (ALI) is common in the intensive care unit (ICU), typically requiring life support ventilation. Survivors often experience anxiety after hospital discharge. We evaluated general anxiety symptoms 3 months after ALI for: (1) associations with patient characteristics and ICU variables, and (2) cross-sectional associations with physical function and quality of life (QOL).

methodsGeneral anxiety was assessed as part of a prospective cohort study recruiting patients from 13 ICUs at four hospitals in Baltimore, MD using the Hospital Anxiety and Depression Scale--Anxiety Subscale (HAD-A), with associations evaluated using multivariable linear and logistic regression models.

resultsOf 152 patients, 38% had a positive screening test for general anxiety (HAD-A≥8). Pre-ICU body mass index and psychiatric comorbidity were associated with general anxiety (OR, 95% confidence interval (CI): 1.06 (1.00, 1.13) and 3.59 (1.25, 10.30), respectively). No ICU-related variables were associated with general anxiety. General anxiety was associated with the number of instrumental ADL dependencies (Spearman's rho=0.22; p=0.004) and worse overall QOL as measured by EQ-5D visual analog scale (VAS) (rho=-0.34; p<0.001) and utility score (rho=-0.30; p<0.001), and by the SF-36 mental health domain (rho=-0.70; p<0.001) and Mental Component Summary score (rho=-0.73; p<0.001).

conclusionMany patients have substantial general anxiety symptoms 3 months after ALI. General anxiety was associated with patient characteristics and impaired physical function and quality of life. Early identification and treatment of general anxiety may enhance physical and emotional function in patients surviving critical illnesses.

Indexed as

Acute Lung InjuryAdultAgedAnxietyCross-Sectional StudiesFemaleHumansIntensive Care UnitsMaleMental HealthMiddle AgedProspective StudiesPsychiatric Status Rating ScalesQuality of LifeSurveys and QuestionnairesSurvivorsAcute lung injury, adultAnxietyCritical careIntensive care unitsPhysical functionQuality of lifeRespiratory distress syndrome, adult

Identifiers

PMID23972420
PMCPMC3981692
OpenAlexW2087360234

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.