Evidence map›Paper›PMID 23972013›Full record

Trial reportParasites & vectors2013

Efficacy of an imidacloprid/flumethrin collar against fleas, ticks and tick-borne pathogens in dogs.

Filipe Dantas-Torres, Gioia Capelli, Alessio Giannelli, Rafael Antonio Nascimento Ramos, Riccardo Paolo Lia, Cinzia Cantacessi, Donato de Caprariis, Anna Sara De Tommasi, Maria Stefania Latrofa, Vita Lacasella and 6 more

Open access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Parasites & vectors, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
5.1field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 59 citations in OpenAlex.

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  15. Blocking transmission of vector-borne diseases.International journal for parasitology. Drugs and drug resistance · 2017
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 5 institutions in 4 countries.

Filipe Dantas-TorresDepartment of Veterinary Medicine, University of Bari, Bari, Valenzano, Italy. domenico.otranto@uniba.it.
Gioia Capelli
Alessio Giannelli
Rafael Antonio Nascimento Ramos
Riccardo Paolo Lia
Cinzia Cantacessi
Donato de Caprariis
Anna Sara De Tommasi
Maria Stefania Latrofa
Vita Lacasella
Viviana Domenica Tarallo
Giancarlo Di Paola
Barbara Qurollo
Edward Breitschwerdt
Dorothee Stanneck
Domenico Otranto
University of Bari Aldo Moro · ITNorth Carolina State University · USBayer (Germany) · DEIstituto Zooprofilattico Sperimentale delle Venezie · ITJames Cook University · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTick-borne diseases comprise a group of maladies that are of substantial medical and veterinary significance. A range of tick-borne pathogens, including diverse species of bacteria and protozoa, can infect both dogs and humans. Hence, the control of tick infestations is pivotal to decrease or prevent tick-borne pathogen transmission. Therefore, different commercial products with insecticidal, repellent or both properties have been developed for use on dogs. Recently, a collar containing a combination of imidacloprid 10% and flumethrin 4.5% has proven effective to prevent tick and flea infestations in dogs under field conditions and the infection by some vector-borne pathogens they transmit under laboratory-controlled conditions.

methodsFrom March 2011 to April 2012, a field study was conducted in a private shelter in southern Italy to assess the efficacy of the imidacloprid/flumethrin collar against tick and flea infestations and to determine if this strategy would decrease tick-borne pathogen transmission in young dogs. A total of 122 animals were enrolled in the study and randomly assigned to group A (n = 64; collared) or group B (n = 58; untreated controls). Dogs were examined monthly for ticks and fleas and systematically tested for selected tick-borne pathogens.

resultsCompared to controls, the collar provided overall efficacies of 99.7% and 100% against tick and flea infestation, respectively. The overall efficacy for the prevention of tick-borne pathogens (i.e., Anaplasma platys and Babesia vogeli) was 91.6%.

conclusionsThis study demonstrates that the imidacloprid/flumethrin collar is efficacious against flea and tick infestation as well as tick-borne pathogen transmission to dogs under field conditions.

Indexed as

Administration, TopicalAnimalsDog DiseasesDogsFemaleFlea InfestationsImidazolesInsecticidesMaleNeonicotinoidsNitro CompoundsPyrethrinsTick-Borne DiseasesTick InfestationsTreatment OutcomeflumethrinimidaclopridImidazolesInsecticidesNeonicotinoidsNitro CompoundsPyrethrins

Identifiers

PMID23972013
PMCPMC3766024
OpenAlexW2161384821

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.