ArticleEvidence-based complementary and alternative medicine : eCAM2013
An In Vivo and In Vitro Evaluation of the Mutual Interactions between the Lung and the Large Intestine.
Article in Evidence-based complementary and alternative medicine : eCAM, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed, 15 citations in OpenAlex.
- Yemazhui () ameliorates lipopolysaccharide-induced acute lung injury modulation of the toll-like receptor 4/nuclear factor kappa-B/nod-like receptor family pyrin domain-containing 3 protein signaling pathway and intestinal flora in rats.Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan · 2024Article
- Age-related hearing loss and its potential drug candidates: a systematic review.Chinese medicine · 2023Review
- Association of lung-intestinal microecology and lung cancer therapy.Chinese medicine · 2023Review
- A Comprehensive Analysis of Microflora and Metabolites in the Development of Ulcerative Colitis into Colorectal Cancer Based on the Lung-Gut Correlation Theory.Molecules (Basel, Switzerland) · 2022Article
- Changes of Intestinal Oxidative Stress, Inflammation, and Gene Expression in Neonatal Diarrhoea Kids.Frontiers in veterinary science · 2021Article
- Biodistribution of andrographolide to assess the interior-exterior relationship between the lung and intestine using microPET.Thoracic cancer · 2020Article
- Jianpi Huatan Tongfu granule alleviates inflammation and improves intestinal flora in patients with acute exacerbation of chronic obstructive pulmonary disease.The Journal of international medical research · 2020Article
- The roles of the TLR/NF‑κB signaling pathway in the mutual interactions between the lung and the large intestine.Molecular medicine reports · 2018Article
- The research of acupuncture effective biomolecules: retrospect and prospect.Evidence-based complementary and alternative medicine : eCAM · 2013Review
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
One of the most important theories of the traditional Chinese medicine is the exterior-interior relationship between the lung and the large intestine; so far, little direct experimental evidence has been reported to support such relationship. Here we for the first time investigated the mutual interactions between the lung and the large intestine by examining the relevancies between the pulmonary functions and the rectal resting pressure in the rat models of asthma and constipation. We also evaluated the effects of the lung homogenate and the large intestine homogenate on the isolated large intestine muscle strip and the isolated tracheal spiral, respectively. Our results showed that the pulmonary resistance and pulmonary compliance were closely related to the rectal resting pressure in the asthmatic rat model, while the rectal resting pressure was much correlated with the pulmonary resistance in the rat model of constipation. Moreover, it was shown that the lung homogenate could specifically contract the isolated large intestine muscle strip. Overall, this study provided new lines of evidence for the theory and highlighted the potential application in the treatment of the corresponding diseases.
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Registered trials
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