Evidence map›Paper›PMID 23970433›Full record

ArticlePediatric blood & cancer2014

Comparison of Latino and non-Latino patients with Ewing sarcoma.

Jeremy Sharib, Andrew Horvai, Florette K Gray Hazard, Heike Daldrup-Link, Robert Goldsby, Neyssa Marina, Steven G DuBois

Open access · greenAbstract readComparative Study
In one paragraph

Article in Pediatric blood & cancer, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.5field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 16 citations in OpenAlex.

  1. Ewing sarcoma of the thumb presenting in a Hispanic patient: A case report.International journal of surgery case reports · 2024
    Article
  2. Article
  3. Article
  4. Article
  5. Death Within 1 Month of Diagnosis in Childhood Cancer: An Analysis of Risk Factors and Scope of the Problem.Journal of clinical oncology : official journal of the American Society of Clinical Oncology · 2017
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Jeremy SharibDepartment of Pediatrics, San Francisco School of Medicine, University of California, San Francisco, California; Department of Pathology, San Francisco School of Medicine, University of California, San Francisco, California.
Andrew Horvai
Florette K Gray Hazard
Heike Daldrup-Link
Robert Goldsby
Neyssa Marina
Steven G DuBois
Stanford University · USUniversity of California, San Francisco · US

Funding

Bone Marrow Micrometastatic Disease in Ewing SarcomaK23CA154530 · NCI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI DUBOIS, STEVEN · 2011 to 2013
$492k
NCI NIH HHS 1K23CA154530NCI NIH HHS K23 CA154530
6 · The paper itself

Abstract

backgroundEwing sarcoma (ES) is a malignancy of bone and soft tissue in children and adults. Previous registry-based studies indicate that Latino patients with ES have inferior outcomes compared to non-Latino patients, though an etiology for this difference could not be identified. To explore possible differences that might underlie this disparity, we conducted a retrospective study to compare clinical characteristics, tumor features, healthcare access, and treatment outcomes between Latino and non-Latino patients with ES.

methodsPrimary data for 218 ES patients treated at two academic medical centers between 1980 and 2010 were collected. Categorical data were compared using Fisher exact tests; Wilcoxon rank-sum tests were used for continuous variables. Survival was estimated using Kaplan-Meier analysis and compared using log-rank testing.

resultsLatino patients were diagnosed at a younger age (P = 0.014). All other clinical and histological data were similar between groups, including radiologic and histologic response to neoadjuvant chemotherapy. Latino patients had lower socioeconomic status (P = 0.001), were less likely to have insurance (P = 0.001), and were more likely to present to the emergency room at onset of symptoms (P = 0.031) rather than to primary care physicians. Five-year event free survival (EFS) and overall survival (OS) were similar between Latino and non-Latino patients (EFS: 60.5% vs. 50.9% P = 0.37; OS: 77.6% vs. 68.6% P = 0.54).

conclusionLatino patients with ES present at a younger age, and have evidence of impaired access to healthcare. Response to initial therapy appears similar between Latino and non-Latino patients.

Indexed as

Healthcare DisparitiesHealth Services AccessibilityAdolescentAdultAntineoplastic Combined Chemotherapy ProtocolsBone NeoplasmsChemotherapy, AdjuvantChildEthnicityFemaleFollow-Up StudiesHispanic or LatinoHumansMaleNeoadjuvant TherapyNeoplasm Metastasiscancer disparitiesethnicityEwing sarcomahispanicLatino

Identifiers

PMID23970433
PMCPMC4206264
OpenAlexW1523671845

What OpenQuestion holds

Textmetadata
LicenceTDM
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.