Evidence map›Paper›PMID 23969801›Full record

ArticleObstetrics and gynecology2013

Enhanced recovery in gynecologic surgery.

Eleftheria Kalogera, Jamie N Bakkum-Gamez, Christopher J Jankowski, Emanuel Trabuco, Jenna K Lovely, Sarah Dhanorker, Pamela L Grubbs, Amy L Weaver, Lindsey R Haas, Bijan J Borah and 4 more

2 registry-linked trialsAbstract read
In one paragraph

Article in Obstetrics and gynecology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 73 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
73citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03126162 nacompletednot on this mapstarted 2017, after this paper: background citation

A Randomized, Controlled Trial Evaluating 2 Techniques of Postoperative Bladder Testing for Patients Undergoing Same-day Total Laparoscopic Hysterectomy

TypeinterventionalSponsorUniversity of PittsburghRan2017 to 2018Enrolled172ConditionsLaparoscopic Hysterectomy, Enhanced Recovery After SurgeryArmsInstilIing normal saline into bladder, Removal of foley catheter
NCT03907033 phase4terminatednot on this mapstarted 2019, after this paper: background citation

Preemptive Local Analgesia With Liposomal Bupivacaine in Vaginal Hysterectomy: A Randomized Controlled Study

TypeinterventionalSponsorMayo ClinicRan2019 to 2021Enrolled28ConditionsVaginal HysterectomyArmsLiposomal bupivacaine, Bupivacaine Hydrochloride
3 · Its place in the literature

Who cites it

73 citing papers in PubMed, 4 syntheses or guidelines pooled it.

  1. Pooled it
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  3. Enhanced recovery versus conventional care in gastric cancer surgery: a meta-analysis of randomized and non-randomized controlled trials.Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association · 2019
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  13. Laparoscopic Posterior Versus Lateral Transversus Abdominis Plane Block in Gynecology.JSLS : Journal of the Society of Laparoendoscopic Surgeons
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  20. How to Reduce Delayed Gastric Emptying After Pancreatoduodenectomy: A Systematic Literature Review and Meta-Analysis.Annals of surgery open : perspectives of surgical history, education, and clinical approaches · 2024
    Article

13 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

14 authors.

Eleftheria KalogeraDivision of Gynecologic Surgery, the Department of Anesthesiology, Hospital Pharmacy Services, the Department of Nursing, the Division of Biomedical Statistics and Informatics, and the Department of Health Sciences, Division of Health Care Policy and Research, Mayo Clinic, Rochester, Minnesota.
Jamie N Bakkum-Gamez
Christopher J Jankowski
Emanuel Trabuco
Jenna K Lovely
Sarah Dhanorker
Pamela L Grubbs
Amy L Weaver
Lindsey R Haas
Bijan J Borah
April A Bursiek
Michael T Walsh
William A Cliby
Sean C Dowdy

Funding

Women's Cancer ProgramP30CA015083 · NCI · MAYO CLINIC ROCHESTER · PI Felicity Enders · 1985 to 2026
$151.3M
Mayo Clinic Interdisciplinary Women's Health Research ProgramK12HD065987 · NICHD · MAYO CLINIC ROCHESTER · PI KANTARCI, KEJAL · 2010 to 2023
$6.7M
NCI NIH HHS P30 CA015083NCI NIH HHS P30 CA 15083NICHD NIH HHS K12 HD065987
6 · The paper itself

Abstract

objectiveTo investigate the effects of enhanced recovery (a multimodal perioperative care enhancement protocol) in patients undergoing gynecologic surgery.

methodsConsecutive patients managed under an enhanced recovery pathway and undergoing cytoreduction, surgical staging, or pelvic organ prolapse surgery between June 20, 2011, and December 20, 2011, were compared with consecutive historical controls (March to December 2010) matched by procedure. Wilcoxon rank-sum, χ, and Fisher's exact tests were used for comparisons. Direct medical costs incurred in the first 30 days were obtained from the Olmsted County Healthcare Expenditure and Utilization Database and standardized to 2011 Medicare dollars.

resultsA total of 241 enhanced recovery women in the case group (81 cytoreduction, 84 staging, and 76 vaginal surgery) were compared with women in the control groups. In the cytoreductive group, patient-controlled anesthesia use decreased from 98.7% to 33.3% and overall opioid use decreased by 80% in the first 48 hours with no change in pain scores. Enhanced recovery resulted in a 4-day reduction in hospital stay with stable readmission rates (25.9% of women in the case group compared with 17.9% of women in the control group) and 30-day cost savings of more than $7,600 per patient (18.8% reduction). No differences were observed in rate (63% compared with 71.8%) or severity of postoperative complications (grade 3 or more: 21% compared with 20.5%). Similar, albeit less dramatic, improvements were observed in the other two cohorts. Ninety-five percent of patients rated satisfaction with perioperative care as excellent or very good.

conclusionsImplementation of enhanced recovery was associated with acceptable pain management with reduced opioids, reduced length of stay with stable readmission and morbidity rates, good patient satisfaction, and substantial cost reductions. LEVEL OF EVIDENCE: II.

Indexed as

AgedFemaleGenital Neoplasms, FemaleGynecologic Surgical ProceduresHumansLength of StayMiddle AgedPatient SatisfactionPelvic Organ ProlapsePerioperative CareRetrospective Studies

Identifiers

PMID23969801
PMCPMC3913481

What OpenQuestion holds

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Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.