A role for IL-17 in age-related macular degeneration.

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

12 citing papers in PubMed, 18 citations in OpenAlex.

1. Dysregulated DNA Methylation inInternational journal of molecular sciences · 2025
   Article
2. A Novel Bispecific Anti-IL17/VEGF Fusion Trap Exhibits Potent and Long-Lasting Inhibitory Effects on the Development of Age-Related Macular Degeneration.Biochemistry research international · 2024
   Article
3. Beyond the Complement Cascade: Insights into Systemic Immunosenescence and Inflammaging in Age-Related Macular Degeneration and Current Barriers to Treatment.Cells · 2023
   Review
4. The role of the adaptive immune system and T cell dysfunction in neurodegenerative diseases.Journal of neuroinflammation · 2022
   Review
5. Contribution of Interleukin-17A to Retinal Degenerative Diseases.Frontiers in immunology · 2022
   Review
6. Molecular Mechanisms Underlying the Therapeutic Role of Vitamin E in Age-Related Macular Degeneration.Frontiers in neuroscience · 2022
   Review
7. IL-17A Damages the Blood-Retinal Barrier through Activating the Janus Kinase 1 Pathway.Biomedicines · 2021
   Article
8. Can innate and autoimmune reactivity forecast early and advance stages of age-related macular degeneration?Autoimmunity reviews · 2017
   Review
9. Fractalkine-CX3CR1 signaling is critical for progesterone-mediated neuroprotection in the retina.Scientific reports · 2017
   Article
10. Association between aqueous humor and vitreous fluid levels of Th17 cell-related cytokines in patients with proliferative diabetic retinopathy.PloS one · 2017
    Article
11. Parainflammation, chronic inflammation, and age-related macular degeneration.Journal of leukocyte biology · 2015
    Review
12. Potential Sources and Roles of Adaptive Immunity in Age-Related Macular Degeneration: Shall We Rename AMD into Autoimmune Macular Disease?Autoimmune diseases · 2014
    Review

Corrections and comments

• Comment on
  Immunology of age-related macular degeneration.2013

Authors and funding

2 authors at 2 institutions in 2 countries.

Funding

No grant is acknowledged in the PubMed record.

Abstract

PubMed holds no abstract for this paper.

Indexed as