ArticleGMS hygiene and infection control2013
Can breathing circuit filters help prevent the spread of influenza A (H1N1) virus from intubated patients?
Article in GMS hygiene and infection control, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it, 23 citations in OpenAlex.
- European consensus recommendations for neonatal and paediatric retrievals of positive or suspected COVID-19 patients.Pediatric research · 2021Guideline
- Review
- Transport Circuit during COVID-19 Crisis: A Simple Modification of the Bain's Circuit for Safety of Healthcare Workers.Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2020Article
- A simple screening test of filtration efficiency for protecting the gas sampling line from coronavirus using fluorescent microspheres.Paediatric anaesthesia · 2020Article
- Opportunities for biomaterials to address the challenges of COVID-19.Journal of biomedical materials research. Part A · 2020Review
- An accessible and economical evacuation system for surgical fumes and pneumoperitoneum in laparoscopy during the SARS-CoV-2 pandemic.The British journal of surgery · 2020Article
- Intubation and Ventilation amid the COVID-19 Outbreak: Wuhan's Experience.Anesthesiology · 2020Article
- Chinese Society of Anesthesiology Expert Consensus on Anesthetic Management of Cardiac Surgical Patients With Suspected or Confirmed Coronavirus Disease 2019.Journal of cardiothoracic and vascular anesthesia · 2020Article
- Clearing the air: an accessible system for suction and safe evacuation of pneumoperitoneum during laparoscopy in patients with COVID-19.The British journal of surgery · 2020Article
- Preparing your intensive care unit for the COVID-19 pandemic: practical considerations and strategies.Critical care (London, England) · 2020Review
- COVID-19: A critical care perspective informed by lessons learnt from other viral epidemics.Anaesthesia, critical care & pain medicine · 2020Article
- A novel sampling method to detect airborne influenza and other respiratory viruses in mechanically ventilated patients: a feasibility study.Annals of intensive care · 2018Article
- Level of respiratory protection against influenza virus.GMS hygiene and infection control · 2013Article
- Airborne Infections and Emergency Surgery: The COVID-19 Pandemic Perspective.Journal of Indian Association of Pediatric SurgeonsReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionIn March 2010, more than 213 countries worldwide reported laboratory confirmed cases of influenza H1N1 infections with at least 16,813 deaths. In some countries, roughly 10 to 30% of the hospitalized patients were admitted to the ICU and up to 70% of those required mechanical ventilation. The question now arises whether breathing system filters can prevent virus particles from an infected patient from entering the breathing system and passing through the ventilator into the ambient air. We tested the filters routinely used in our institution for their removal efficacy and efficiency for the influenza virus A H1N1 (A/PR/8/34).
methodsLaboratory investigation of three filters (PALL Ultipor(®) 25, Ultipor(®) 100 and Pall BB50T Breathing Circuit Filter, manufactured by Pall Life Sciences) using a monodispersed aerosol of human influenza A (H1N1) virus in an air stream model with virus particles quantified as cytopathic effects in cultured canine kidney cells (MDCK).
resultsThe initial viral load of 7.74±0.27 log10 was reduced to a viral load of ≤2.43 log10, behind the filter. This represents a viral filtration efficiency of ≥99.9995%.
conclusionThe three tested filters retained the virus input, indicating that their use in the breathing systems of intubated and mechanically ventilated patients can reduce the risk of spreading the virus to the breathing system and the ambient air.
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