Evidence map›Paper›PMID 23967138›Full record

ArticlePloS one2013

Using the electronic medical record to identify community-acquired pneumonia: toward a replicable automated strategy.

Sylvain DeLisle, Bernard Kim, Janaki Deepak, Tariq Siddiqui, Adi Gundlapalli, Matthew Samore, Leonard D'Avolio

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 2 pooled it
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 2 syntheses or guidelines pooled it, 40 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
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  6. Article
  7. Host genetic effects in pneumonia.American journal of human genetics · 2021
    Article
  8. Article
  9. Review
  10. Article
  11. Article
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  14. The power of data mining in diagnosis of childhood pneumonia.Journal of the Royal Society, Interface · 2016
    Article
  15. How next-generation sequencing and multiscale data analysis will transform infectious disease management.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2015
    Article
  16. Article
  17. Article
  18. Article
  19. Natural Language Processing for EHR-Based Computational Phenotyping.IEEE/ACM transactions on computational biology and bioinformatics
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 1 country.

Sylvain DeLisleDepartment of Medicine, Veterans Affairs Maryland Health Care System, Baltimore, Maryland, USA. sdelisle@umaryland.edu
Bernard Kim
Janaki Deepak
Tariq Siddiqui
Adi Gundlapalli
Matthew Samore
Leonard D'Avolio
University of Maryland, Baltimore · USVA Maryland Health Care System · USHarvard University · USUniversity of Utah · USVA Salt Lake City Healthcare System · US

Funding

Developing a Bioterrorism Syndromic Surveillance SystemR01CI000098 · CI · JOHNS HOPKINS UNIVERSITY · PI PERL, TRISH M · 2003 to 2005
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HSRD VA HIR 10-001NCPDCID CDC HHS R01 CI000098PHITPO CDC HHS 5U38HK000013-02PHITPO CDC HHS U38 HK000013
6 · The paper itself

Abstract

backgroundTimely information about disease severity can be central to the detection and management of outbreaks of acute respiratory infections (ARI), including influenza. We asked if two resources: 1) free text, and 2) structured data from an electronic medical record (EMR) could complement each other to identify patients with pneumonia, an ARI severity landmark.

methodsA manual EMR review of 2747 outpatient ARI visits with associated chest imaging identified x-ray reports that could support the diagnosis of pneumonia (kappa score  = 0.88 (95% CI 0.82∶0.93)), along with attendant cases with Possible Pneumonia (adds either cough, sputum, fever/chills/night sweats, dyspnea or pleuritic chest pain) or with Pneumonia-in-Plan (adds pneumonia stated as a likely diagnosis by the provider). The x-ray reports served as a reference to develop a text classifier using machine-learning software that did not require custom coding. To identify pneumonia cases, the classifier was combined with EMR-based structured data and with text analyses aimed at ARI symptoms in clinical notes.

results370 reference cases with Possible Pneumonia and 250 with Pneumonia-in-Plan were identified. The x-ray report text classifier increased the positive predictive value of otherwise identical EMR-based case-detection algorithms by 20-70%, while retaining sensitivities of 58-75%. These performance gains were independent of the case definitions and of whether patients were admitted to the hospital or sent home. Text analyses seeking ARI symptoms in clinical notes did not add further value.

conclusionSpecialized software development is not required for automated text analyses to help identify pneumonia patients. These results begin to map an efficient, replicable strategy through which EMR data can be used to stratify ARI severity.

Indexed as

Community-Acquired InfectionsElectronic Health RecordsPneumoniaAdolescentAdultAgedAged, 80 and overAlgorithmsFemaleHumansMaleMiddle AgedOutpatientsReproducibility of ResultsSoftwareYoung Adult

Identifiers

PMID23967138
PMCPMC3742728
OpenAlexW2120757740

What OpenQuestion holds

Textmetadata
LicenceCC0
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.