ArticleFrontiers in plant science2013
Mitochondrial ferritin is a functional iron-storage protein in cucumber (Cucumis sativus) roots.
Article in Frontiers in plant science, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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13 citing papers in PubMed, 29 citations in OpenAlex.
- Plant Iron Research in African Countries: Current "Hot Spots", Approaches, and Potentialities.Plants (Basel, Switzerland) · 2023Review
- Advanced characterization of biomineralization at plaque layer and inside rice roots amended with iron- and silica-enhanced biochar.Scientific reports · 2021Article
- Differential iron management in monocotyledon and dicotyledon plants from the Río Tinto basin.Protoplasma · 2020Article
- Metal tolerance protein MTP6 affects mitochondrial iron and manganese homeostasis in cucumber.Journal of experimental botany · 2019Article
- Cellular Fractionation and Nanoscopic X-Ray Fluorescence Imaging Analyses Reveal Changes of Zinc Distribution in Leaf Cells of Iron-Deficient Plants.Frontiers in plant science · 2018Article
- Prospecting for Microelement Function and Biosafety Assessment of Transgenic Cereal Plants.Frontiers in plant science · 2018Review
- Insights into Resistance to Fe Deficiency Stress from a Comparative Study ofFrontiers in plant science · 2017Article
- Dealing with iron metabolism in rice: from breeding for stress tolerance to biofortification.Genetics and molecular biology · 2017Article
- Characterization of human mitochondrial ferritin promoter: identification of transcription factors and evidences of epigenetic control.Scientific reports · 2016Article
- Article
- Reduction in mitochondrial iron alleviates cardiac damage during injury.EMBO molecular medicine · 2016Article
- Article
- Cellular iron homeostasis and metabolism in plant.Frontiers in plant science · 2013Article
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3 authors at 1 institution in 1 country.
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Abstract
In plants, intracellular Fe trafficking must satisfy chloroplasts' and mitochondrial demands for Fe without allowing its accumulation in the organelles in dangerous redox-active forms. Protein ferritin is involved in such homeostatic control, however its functional role in mitochondria, differently from its role in chloroplasts, is still matter of debate. To test ferritin functionality as a 24-mer Fe-storage complex in mitochondria, cucumber seedlings were grown under different conditions of Fe supply (excess, control, deficiency) and mitochondria were purified from the roots. A ferritin monomer of around 25 KDa was detected by SDS-PAGE in Fe-excess root mitochondria, corresponding to the annotated Csa5M215130/XP_004163524 protein: such a monomer is barely detectable in the control mitochondria and not at all in the Fe-deficient ones. Correspondingly, the ferritin 24-mer complex is abundant in root mitochondria from Fe-excess plants and it stores Fe as Fe(III): such a complex is also detectable, though to a much smaller extent, in control mitochondria, but not in Fe-deficient ones. Cucumber ferritin Csa5M215130/XP_004163524 is therefore a functional Fe(III)-store in root mitochondria and its abundance is dependent on the Fe nutritional status of the plant.
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