ArticleFrontiers in microbiology2013
Biotic acts of antibiotics.
Article in Frontiers in microbiology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
20 citing papers in PubMed.
- Bioprospecting Indoor Bacteria Producing Bioactive Metabolites.Environmental microbiology reports · 2026Article
- Targeting Bacterial Infections in Periodontal Disease: From Conventional Antibiotics to Next-Generation Therapeutics.Antibiotics (Basel, Switzerland) · 2026Review
- Assessing the Ecological Roles of Resistomes within Microbial Communities in Antibiotic-contaminated Ecosystems.Microbial ecology · 2026Review
- Aluminium-doped Carbon Dots for the Simultaneous Selective Detection of Five Tetracycline Antibiotics.Journal of fluorescence · 2025Article
- Menadione as Antibiotic Adjuvant AgainstAntibiotics (Basel, Switzerland) · 2025Article
- Systemic Response to Infection Induces Long-Term Cognitive Decline: Neuroinflammation and Oxidative Stress as Therapeutical Targets.Frontiers in neuroscience · 2021Review
- Clinical Biofilm Ring TestPathogens (Basel, Switzerland) · 2020Article
- Study of the structural, chemical descriptors and optoelectronic properties of the drugs Hydroxychloroquine and Azithromycin.Heliyon · 2020Review
- Erythromycin acts through the ghrelin receptor to attenuate inflammatory responses in chondrocytes and maintain joint integrity.Biochemical pharmacology · 2019Article
- Environmental Triggers of Autoreactive Responses: Induction of Antiphospholipid Antibody Formation.Frontiers in immunology · 2019Review
- PA5470 Counteracts Antimicrobial Effect of Azithromycin by Releasing Stalled Ribosome in Pseudomonas aeruginosa.Antimicrobial agents and chemotherapy · 2018Article
- Dendritic cell expression of the signaling molecule TRAF6 is required for immune tolerance in the lung.International immunology · 2017Article
- Editorial: Phage Therapy: Past, Present and Future.Frontiers in microbiology · 2017Article
- Macrolides and associated antibiotics based on similar mechanism of action like lincosamides in malaria.Malaria journal · 2016Article
- PA3297 Counteracts Antimicrobial Effects of Azithromycin in Pseudomonas aeruginosa.Frontiers in microbiology · 2016Article
- Ecology of Anti-Biofilm Agents I: Antibiotics versus Bacteriophages.Pharmaceuticals (Basel, Switzerland) · 2015Review
- Responses of Pseudomonas aeruginosa to antimicrobials.Frontiers in microbiology · 2014Review
- Low-dose antibiotics: current status and outlook for the future.Frontiers in microbiology · 2014Article
- Antivirulence activity of azithromycin in Pseudomonas aeruginosa.Frontiers in microbiology · 2014Review
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Biological functions of antibiotics are not limited to killing. The most likely function of antibiotics in natural microbial ecosystems is signaling. Does this signaling function of antibiotics also extend to the eukaryotic - in particular mammalian - cells? In this review, the host modulating properties of three classes of antibiotics (macrolides, tetracyclines, and β-lactams) will be briefly discussed. Antibiotics can be effective in treatment of a broad spectrum of diseases and pathological conditions other than those of infectious etiology and, in this capacity, may find widespread applications beyond the intended antimicrobial use. This use, however, should not compromise the primary function antibiotics are used for. The biological background for this inter-kingdom signaling is also discussed.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.