ArticleFrontiers in psychiatry2013
Polysubstance use in cannabis users referred for treatment: drug use profiles, psychiatric comorbidity and cannabis-related beliefs.
Article in Frontiers in psychiatry, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers.
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Who cites it
42 citing papers in PubMed.
- Service utilization patterns in cocaine use disorder: A data-driven study.Drug and alcohol dependence reports · 2026Article
- Neuroinflammatory-related biomarkers and psychiatric symptom changes in substance use disorder: a South African cohort study.BMC psychiatry · 2026Article
- Memory impairment and chronic high-dose Δ9-THC/cannabis exposure: a narrative review of molecular mechanisms underlying neurotoxic effects.Psychopharmacology · 2026Review
- Trends in polysubstance use in the Croatian general population: evidence from 2011-2023 national surveys.Croatian medical journal · 2026Article
- Sex differences in factors associated with cannabis use among emerging adults.Frontiers in psychology · 2026Article
- Cannabinoids and Adverse Convulsive Effects: A Pharmacovigilance and Addictovigilance Analysis of Cases Reported in France.Fundamental & clinical pharmacology · 2025Article
- Major Depression in Comorbidity with Substance use Disorders: Patients' Features and Clinical-Neurobiological Rationale of Antidepressant Treatments.Current neuropharmacology · 2025Review
- Polysubstance use by sexual identity among US adults, 2021.Preventive medicine · 2023Article
- Article
- Altered functional connectivity and oscillatory dynamics in polysubstance and cannabis only users during visuospatial processing.Psychopharmacology · 2023Article
- Patterns of polysubstance use and clinical comorbidity among persons seeking substance use treatment: An observational study.Journal of substance use and addiction treatment · 2023Observational
- Cannabis Use and Risk of Acute Kidney Injury in Patients with Advanced Chronic Kidney Disease Transitioning to Dialysis.Cannabis and cannabinoid research · 2023Observational
- Profiles of quality of outpatient care use, associated sociodemographic and clinical characteristics, and adverse outcomes among patients with substance-related disorders.Substance abuse treatment, prevention, and policy · 2023Article
- Resilience profiles predict polysubstance use in adolescents with a history of childhood maltreatment.Addiction research & theory · 2023Article
- Polysubstance use in young people accessing residential and day-treatment services for substance use: substance use profiles, psychiatric comorbidity and treatment completion.Addiction (Abingdon, England) · 2022Article
- Specific polysubstance use patterns predict relapse among patients entering opioid use disorder treatment.Drug and alcohol dependence reports · 2022Article
- Can cannabis kill? Characteristics of deaths following cannabis use in England (1998-2020).Journal of psychopharmacology (Oxford, England) · 2022Article
- Prevalence and sociodemographic factors associated with polysubstance use: analysis of a population-based survey in Jamaica.BMC psychiatry · 2022Article
- Clinical management of cannabis withdrawal.Addiction (Abingdon, England) · 2022Review
- Altered cerebellar-cortical resting-state functional connectivity in cannabis users.Journal of psychopharmacology (Oxford, England) · 2021Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPopulation-based surveys demonstrate cannabis users are more likely to use both illicit and licit substances, compared with non-cannabis users. Few studies have examined the substance use profiles of cannabis users referred for treatment. Co-existing mental health symptoms and underlying cannabis-related beliefs associated with these profiles remains unexplored.
methodsComprehensive drug use and dependence severity (Severity of Dependence Scale-Cannabis) data were collected on a sample of 826 cannabis users referred for treatment. Patients completed the General Health Questionnaire, Cannabis Expectancy Questionnaire, Cannabis Refusal Self-Efficacy Questionnaire, and Positive Symptoms and Manic-Excitement subscales of the Brief Psychiatric Rating Scale. Latent class analysis was performed on last month use of drugs to identify patterns of multiple drug use. Mental health comorbidity and cannabis beliefs were examined by identified drug use pattern.
resultsA three-class solution provided the best fit to the data: (1) cannabis and tobacco users (n = 176), (2) cannabis, tobacco, and alcohol users (n = 498), and (3) wide-ranging substance users (n = 132). Wide-ranging substance users (3) reported higher levels of cannabis dependence severity, negative cannabis expectancies, lower opportunistic, and emotional relief self-efficacy, higher levels of depression and anxiety and higher manic-excitement and positive psychotic symptoms.
conclusionIn a sample of cannabis users referred for treatment, wide-ranging substance use was associated with elevated risk on measures of cannabis dependence, co-morbid psychopathology, and dysfunctional cannabis cognitions. These findings have implications for cognitive-behavioral assessment and treatment.
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