ArticleThe Malaysian journal of medical sciences : MJMS2013
Isolation of Extended Spectrum β-lactamase (ESBL) Producing Bacteria from Urban Surface Waters in Malaysia.
Article in The Malaysian journal of medical sciences : MJMS, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed.
- Prevalence of ESBL-producingOne health (Amsterdam, Netherlands) · 2025Review
- Occurrence and molecular detection of antibiotic-resistant genes inSustainable microbiology · 2025Article
- Article
- Spread Patterns of Antibiotic Resistance in Faecal Indicator Bacteria Contaminating an Urbanized Section of the Brda River.Microbial ecology · 2021Article
- Occurrence and Characteristics of Extended-Spectrum β-Lactamase-ProducingPathogens (Basel, Switzerland) · 2020Article
- Resistotyping and extended-spectrum beta-lactamase genes amongNew microbes and new infections · 2020Article
- Prevalence of antibiotic-resistant, toxic metal-tolerant and biofilm-forming bacteria in hospital surroundings.Environmental analysis, health and toxicology · 2020Article
- Draft Genome Sequence of the Extended-Spectrum β-Lactamase-Producing Escherichia coli Isolate INF13/18/A, Recovered from Kelantan, Malaysia.Microbiology resource announcements · 2020Article
- Antimicrobial Resistance, Virulence Factors, and Pathotypes ofPathogens (Basel, Switzerland) · 2019Article
- Detection of different β-lactamases encoding genes, including blaEnvironmental monitoring and assessment · 2018Article
- Detection of β-lactamase encoding genes in feces, soil and water from a Brazilian pig farm.Environmental monitoring and assessment · 2018Article
- Article
- Clonal Diversity of ESBL-Producing Escherichia coli Isolated from Environmental, Human and Food Samples.International journal of environmental research and public health · 2017Article
- Genetic Investigation of Beta-Lactam Associated Antibiotic Resistance AmongThe open microbiology journal · 2017Article
- Antimicrobial Susceptibility of Klebsiella pneumoniae and Escherichia coli with Extended-Spectrum β-lactamase associated Genes in Hospital Tengku Ampuan Afzan, Kuantan, Pahang.The Malaysian journal of medical sciences : MJMS · 2016Article
- A Review of SHV Extended-Spectrum β-Lactamases: Neglected Yet Ubiquitous.Frontiers in microbiology · 2016Review
- Detection of Extended Spectrum Beta-Lactamases Resistance Genes among Bacteria Isolated from Selected Drinking Water Distribution Channels in Southwestern Nigeria.BioMed research international · 2016Article
- Antibiotic Resistance Patterns of Pseudomonas spp. Isolated from the River Danube.Frontiers in microbiology · 2016Article
- TEM mediated extended spectrum cephalosporin resistance in clinical & environmental isolates of Gram negative bacilli: A report from northeast India.The Indian journal of medical research · 2015Article
- Prevalence of antibiotic resistant bacteria in healthy adults, foods, food animals, and the environment in selected areas in Thailand.Pathogens and global health · 2014Article
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThis was a preliminary study to test for the presence of multiple antibiotic-resistant extended spectrum β-lactamase (ESBL) producing bacteria in Malaysian urban surface waters. Although the literature review revealed several published papers on clinical ESBL isolates in Malaysia, none were found on ESBL isolates obtained from local surface waters.
methodsIsolated bacterial species were tested for resistance to cefotaxime, amoxicillin/clavulanate and aztreonam, and susceptibility to imipenem and meropenem using antibiotic susceptibility testing (AST) by disc diffusion. This served as a screening step to detect bacteria that could be potential ESBL species. 16S ribose ribonucleic acid (rRNA) polymerase chain reaction (PCR) testing with two clusters of bla (β-lactamase) gene primers was used to test for the bla genes CTX-M (Groups 1, 2, 9), OXA-1, SHV and TEM.
resultsA total of 19 isolates were found, possessing at least one of the bla genes tested for. There was a relatively high occurrence of CTX-M genes (84.2%) among these, followed by TEM genes (47.4%). The isolates were identified as Enterobacteriaceae (89.5%), predominantly Escherichia coli and Klebsiella pneumoniae.
conclusionThere appears to be a high occurrence of ESBL-bacteria in local surface waters, among these being opportunistic pathogens. The persistence and spread of these species in the environment poses a threat to exposed human populations.
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23966820PMC3743977What OpenQuestion holds
Registered trials
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