ArticleCell cycle (Georgetown, Tex.)2013
Hypothalamic inflammation and GnRH in aging development.
Article in Cell cycle (Georgetown, Tex.), 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed.
- Brain senescence drives sarcopenia-like transcriptomic remodeling in skeletal muscle.GeroScience · 2026Article
- Irradiation-induced brain senescence accelerates cardiac aging via systemic mechanisms: insights from transcriptomic profiling.GeroScience · 2026Article
- Targeting the hypothalamus for modeling age-related DNA methylation and developing OXT-GnRH combinational therapy against Alzheimer's disease-like pathologies in male mouse model.Nature communications · 2024Article
- Rationale, study design and implementation of the LUCINDA Trial: Leuprolide plus Cholinesterase Inhibition to reduce Neurologic Decline in Alzheimer's.Contemporary clinical trials · 2021Article
- Article
- Hypothalamic gene transfer of BDNF promotes healthy aging in mice.Aging cell · 2019Article
- Neuroendocrinology of reproduction: Is gonadotropin-releasing hormone (GnRH) dispensable?Frontiers in neuroendocrinology · 2019Review
- Leukemia Inhibitory Factor Represses GnRH Gene Expression via cFOS during Inflammation in Male Mice.Neuroendocrinology · 2019Article
- Central Leptin and Tumor Necrosis Factor-α (TNFα) in Diurnal Control of Blood Pressure and Hypertension.The Journal of biological chemistry · 2016Article
- Ring Finger Protein 11 Inhibits Melanocortin 3 and 4 Receptor Signaling.Frontiers in endocrinology · 2016Article
- Transient early food restriction leads to hypothalamic changes in the long-lived crowded litter female mice.Physiological reports · 2015Article
- Maintenance of homeostasis in the aging hypothalamus: the central and peripheral roles of succinate.Frontiers in endocrinology · 2015Review
- Hypothalamic microinflammation: a common basis of metabolic syndrome and aging.Trends in neurosciences · 2015Review
- Aging and brain rejuvenation as systemic events.Journal of neurochemistry · 2015Review
- Obesity- and aging-induced excess of central transforming growth factor-β potentiates diabetic development via an RNA stress response.Nature medicine · 2014Article
- Aging is not programmed: genetic pseudo-program is a shadow of developmental growth.Cell cycle (Georgetown, Tex.) · 2013Review
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2 authors.
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Abstract
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.