Evidence map›Paper›PMID 23965261›Full record

Trial reportPsychiatry2013

Impact of motivational pharmacotherapy on treatment retention among depressed Latinos.

Roberto Lewis-Fernández, Iván C Balán, Sapana R Patel, J Arturo Sánchez-Lacay, César Alfonso, Magdaliz Gorritz, Carlos Blanco, Andrew Schmidt, Huiping Jiang, Franklin Schneier and 1 more

Registry-linked trialAbstract readClinical Trial
In one paragraph

Trial report in Psychiatry, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03499600 (Improving Satisfaction, Engagement and Clinical Outcomes Among Traditionally Underserved Children Through Cultural Formulation), which is not on this map. Cited by 18 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 4 pooled it
7.3field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03499600 nacompletednot on this mapstarted 2017, after this paper: background citation

Improving Satisfaction, Engagement and Clinical Outcomes Among Traditionally Underserved Children Through Cultural Formulation

TypeinterventionalSponsorFlorida International UniversityRan2017 to 2019Enrolled89ConditionsDisruptive BehaviorArmsClinical Assessment and CFI, Clinical Assessment
3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 4 syntheses or guidelines pooled it, 40 citations in OpenAlex.

  1. Pooled it
  2. Motivational Interviewing in Ethnic Populations.Journal of immigrant and minority health · 2020
    Pooled it
  3. Pooled it
  4. Pooled it
  5. Trial
  6. Trial
  7. Article
  8. Abating Ambivalence: Motivating Depressed Patients for Treatment.Focus (American Psychiatric Publishing) · 2020
    Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Racial and Ethnic Disparity in Major Depressive Disorder.Journal of racial and ethnic health disparities · 2016
    Article
  14. Article
  15. Article
  16. Article
  17. Review
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Roberto Lewis-FernándezDepartment of Psychiatry, Columbia University, New York State Psychiatric Institute, USA.
Iván C Balán
Sapana R Patel
J Arturo Sánchez-Lacay
César Alfonso
Magdaliz Gorritz
Carlos Blanco
Andrew Schmidt
Huiping Jiang
Franklin Schneier
Theresa B Moyers
New York State Psychiatric InstituteUniversity of New Mexico · US

Funding

IMPLEMENTATION RESEARCH INSTITUTE FOR MENTAL HEALTH SERVICES IRI-MHSR25MH080916 · NIMH · WASHINGTON UNIVERSITY · PI Byron James Powell · 2009 to 2026
$3.7M
Motivational Antidepressant Therapy for HispanicsR01MH077226 · NIMH · NEW YORK STATE PSYCHIATRIC INSTITUTE DBA RESEARCH FOUNDATION FOR MENTAL HYGIENE, INC · PI LEWIS-FERNANDEZ, ROBERTO · 2007 to 2011
$2.9M
Improving the Effectiveness of Treatment for Depression in HispanicsR01MH076051 · NIMH · NEW YORK STATE PSYCHIATRIC INSTITUTE DBA RESEARCH FOUNDATION FOR MENTAL HYGIENE, INC · PI BLANCO, CARLOS · 2008 to 2012
$2.8M
Bridging Efficacy and Effectiveness in Drug Abuse TreatmentK02DA023200 · NIDA · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI BLANCO, CARLOS · 2008 to 2012
$618k
Improving Hispanic Retention in Antidepressant TherapyR21MH066388 · NIMH · NEW YORK STATE PSYCHIATRIC INSTITUTE · PI LEWIS-FERNANDEZ, ROBERTO · 2002 to 2003
$285k
NIDA NIH HHS DA023200NIDA NIH HHS K02 DA023200NIMH NIH HHS MH076051NIMH NIH HHS R01 MH076051NIMH NIH HHS R01 MH 077226NIMH NIH HHS R01 MH077226NIMH NIH HHS R21 MH 066388NIMH NIH HHS R21 MH066388NIMH NIH HHS R25 MH080916
6 · The paper itself

Abstract

Compared to non-Latino Whites, U.S. racial/ethnic minority groups show higher non-adherence with outpatient antidepressant therapy, including lower retention, despite adjusting for sociodemographic and insurance covariates. Culturally salient concerns about antidepressants leading to ambivalence about treatment engagement may contribute to this discrepancy. To improve treatment adherence among depressed Latinos, we developed motivational pharmacotherapy, a novel approach that combines motivational interviewing, standard pharmacotherapy, and attention to Latino cultural concerns about antidepressants. This 12-week, open-trial, pre-post pilot study assessed the impact of motivational pharmacotherapy on antidepressant therapy retention, response (symptoms, functioning, and quality of life), and visit duration among n = 50 first-generation Latino outpatients with major depressive disorder. At study endpoint, 20% of patients discontinued treatment, with a mean therapy duration of 74.2 out of 84 days. Patients' symptoms, psychosocial functioning, and quality of life improved significantly. Mean visit length was 36.7 minutes for visit 1 and 24.3 minutes for subsequent visits, compatible with use in community clinics. Responder and remitter rates were 82% and 68%. Compared to published Latino proportions of non-retention (32-53%) and previous studies at our clinic with similar samples and medications (36-46%), Motivational pharmacotherapy appears to improve Latino retention in antidepressant therapy and should be investigated further in controlled designs.

Indexed as

Minority GroupsMotivational InterviewingAcculturationAdultAntidepressive AgentsCombined Modality TherapyFemaleHealthcare DisparitiesHispanic or LatinoHumansIntention to Treat AnalysisMajor Depressive DisorderMaleOutcome Assessment, Health CarePatient CompliancePhysician-Patient RelationsAntidepressive Agents

Identifiers

PMID23965261
PMCPMC4331057
OpenAlexW2002688026

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.