ArticleArthritis research & therapy2013
SCORE and REGICOR function charts underestimate the cardiovascular risk in Spanish patients with rheumatoid arthritis.
Article in Arthritis research & therapy, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.
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Who cites it
20 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Cardiovascular disease risk scores in the current practice: which to use in rheumatoid arthritis?Journal of medicine and lifePooled it
- Performance of the new PREVENT score for indicating subclinical atherosclerosis in rheumatoid arthritis.Rheumatology (Oxford, England) · 2025Article
- Post-Translational Modifications of Lipoproteins: Emerging Players Linking Inflammation and Cardiovascular Disease in Rheumatoid Arthritis-A Narrative Review.International journal of molecular sciences · 2025Review
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- The Role of Visualization in Estimating Cardiovascular Disease Risk: Scoping Review.JMIR public health and surveillance · 2024Article
- Dickkopf-Related Protein 1 (DKK-1) as a Possible Link between Bone Erosions and Increased Carotid Intima-Media Thickness in Psoriatic Arthritis: An Ultrasound Study.International journal of molecular sciences · 2023Article
- Cardiovascular disease risk evaluation impact in patients with rheumatoid arthritis.American journal of preventive cardiology · 2022Article
- Enthesitis and joint erosions are disease traits associated with cardiovascular risk in psoriatic arthritis.Clinical rheumatology · 2020Observational
- Effects of disease activity on lipoprotein levels in patients with early arthritis: can oxidized LDL cholesterol explain the lipid paradox theory?Arthritis research & therapy · 2020Article
- The improvement in aerobic capacity, disease activity, and function in patients with rheumatoid arthritis following cardiac rehabilitation program: A single-center, controlled study.Turkish journal of physical medicine and rehabilitation · 2020Article
- Cardiometabolic comorbidities in RA and PsA: lessons learned and future directions.Nature reviews. Rheumatology · 2019 · on this mapReview
- Cardiovascular and Metabolic Comorbidities in Rheumatoid Arthritis.Current rheumatology reports · 2018Review
- Microvascular endothelial dysfunction in rheumatoid arthritis.Nature reviews. Rheumatology · 2018Review
- Cardiovascular risk in patients with rheumatoid arthritis.Seminars in immunopathology · 2017Review
- Relationship between hsTnI and coronary stenosis in asymptomatic women with rheumatoid arthritis.BMC cardiovascular disorders · 2016Article
- Improving cardiovascular health and metabolic comorbidities in patients with psoriatic arthritis.International journal of clinical rheumatology · 2015Article
- Management of hyperlipidemia among patients with rheumatoid arthritis in the primary care setting.BMC musculoskeletal disorders · 2015Article
- The ability of the 2013 American College of Cardiology/American Heart Association cardiovascular risk score to identify rheumatoid arthritis patients with high coronary artery calcification scores.Arthritis & rheumatology (Hoboken, N.J.) · 2015Article
- Cardiovascular involvement in autoimmune diseases.BioMed research international · 2014Review
- Utility of different cardiovascular disease prediction models in rheumatoid arthritis.Journal of medicine and lifeArticle
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionOur objective was to determine which one of the two function charts available in Spain to calculate cardiovascular (CV) risk, Systematic COronary Risk Evaluation (SCORE) or Framingham-REgistre GIroní del COR (REGICOR), should be used in patients with rheumatoid arthritis (RA).
methodsA series of RA patients seen over a one-year period without history of CV events were assessed. SCORE, REGICOR, modified (m)SCORE and mREGICOR according to the European League Against Rheumatism (EULAR) recommendations were applied. Carotid ultrasonography (US) was performed. Carotid intima-media thickness (cIMT) > 0.90 mm and/or carotid plaques were used as the gold standard test for severe subclinical atherosclerosis and high CV risk (US+). The area under the receiver operating curves (AUC) for the predicted risk for mSCORE and mREGICOR were calculated according to the presence of severe carotid US findings (US+).
resultsWe included 370 patients (80% women; mean age 58.9 ± 13.7 years); 36% had disease duration of 10 years or more; rheumatoid factor (RF) and/or anticyclic citrullinated peptide (anti-CCP) were positive in 68%; and 17% had extra-articular manifestations. The EULAR multiplier factor was used in 122 (33%) of the patients. The mSCORE was 2.16 ± 2.49% and the mREGICOR 4.36 ± 3.46%. Regarding US results, 196 (53%) patients were US+. The AUC mSCORE was 0.798 (CI 95%: 0.752 to 0.844) and AUC mREGICOR 0.741 (95% CI; 0.691 to 0.792). However, mSCORE and mREGICOR failed to identify 88% and 91% of US+ patients. More than 50% of patients with mSCORE ≥1% or mREGICOR >1% were US+.
conclusionsNeither of these two function charts was useful in estimating CV risk in Spanish RA patients.
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