ReviewDeutsches Arzteblatt international2013
The diagnosis, treatment and follow-up of extracranial carotid stenosis.
Review in Deutsches Arzteblatt international, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
36 citing papers in PubMed, 1 synthesis or guideline pooled it, 93 citations in OpenAlex.
- Diagnosis, Treatment and Follow-up in Extracranial Carotid Stenosis.Deutsches Arzteblatt international · 2020Pooled it
- Diagnosis of extracranial carotid stenosis by MRA of the brain.Scientific reports · 2021Trial
- Risk of Inhospital Stroke or Death Is Associated With Age But Not Sex in Patients Treated With Carotid Endarterectomy for Asymptomatic or Symptomatic Stenosis in Routine Practice: Secondary Data Analysis of the Nationwide German Statutory Quality Assurance Database From 2009 to 2014.Journal of the American Heart Association · 2017Trial
- Analysis of risk factors for carotid artery plaque in asymptomatic adults.BMC cardiovascular disorders · 2024Article
- [Results of a single center vascular screening program in Germany].Chirurgie (Heidelberg, Germany) · 2023Article
- Synthetic role of miR-200b-3p, ABCDBrain and behavior · 2022Article
- Intraoperative completion studies in carotid endarterectomy: systematic review and meta-analysis of techniques and outcomes.Annals of translational medicine · 2021Article
- High-Frame Rate Vector Flow Imaging Technique: Initial Application in Evaluating the Hemodynamic Changes of Carotid Stenosis Caused by Atherosclerosis.Frontiers in cardiovascular medicine · 2021Article
- Carotid endarterectomy versus conservative management of the asymptomatic carotid stenosis before coronary artery bypass grafting: a retrospective study.BMC cardiovascular disorders · 2020Article
- Article
- Monocyte/lymphocyte ratio is associated with carotid stenosis in ischemic stroke: A retrospective analysis.Brain and behavior · 2019Article
- Risk factors associated with extracranial atherosclerosis in old patients with acute ischemic stroke.Scientific reports · 2018Article
- Ideal Cardiovascular Health Metrics Associated with Reductions in the Risk of Extracranial Carotid Artery Stenosis: a Population-based Cohort Study.Scientific reports · 2018Article
- [Potential errors in vascular patients due to anatomical variants of the ascending pharyngeal artery].Der Nervenarzt · 2018Article
- Risk of Stroke or Death Is Associated With the Timing of Carotid Artery Stenting for Symptomatic Carotid Stenosis: A Secondary Data Analysis of the German Statutory Quality Assurance Database.Journal of the American Heart Association · 2018Observational
- Regional frequency variation of revascularization procedures for carotid stenosis in Germany: Secondary data analysis of DRG data from 2012 to 2014.Gefasschirurgie : Zeitschrift fur vaskulare und endovaskulare Chirurgie : Organ der Deutschen und der Osterreichischen Gesellschaft fur Gefasschirurgie unter Mitarbeit der Schweizerischen Gesellschaft fur Gefasschirurgie · 2018Article
- Comparison of long-term results of carotid endarterectomy for asymptomatic carotid artery stenosis.Gefasschirurgie : Zeitschrift fur vaskulare und endovaskulare Chirurgie : Organ der Deutschen und der Osterreichischen Gesellschaft fur Gefasschirurgie unter Mitarbeit der Schweizerischen Gesellschaft fur Gefasschirurgie · 2018Review
- Carotid Stenting in Neuroradiology : A Short Journey from the Past to Current Debates.Clinical neuroradiology · 2017Review
- Surgical and Endovascular Treatment of Extracranial Carotid Stenosis.Deutsches Arzteblatt international · 2017Article
- Contrast-enhanced ultrasound of the carotid system: a review of the current literature.Journal of ultrasound · 2017Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundExtracranial atherosclerotic lesions of the carotid bifurcation cause 10% to 20% of all cases of cerebral ischemia. Until now, there have been no comprehensive evidence- and consensus-based recommendations for the management of patients with extracranial carotid stenosis in Germany and Austria.
methodsThe literature was systematically searched for pertinent publications (1990-2011). On the basis of 182 randomized clinical trials (RCTs) and 308 systematic reviews, 30 key questions were answered and evidence-based recommendations were issued.
resultsThe prevalence of extracranial carotid stenosis is more than 5% from age 65 onward. Men are affected twice as frequently as women. The most important diagnostic technique is Doppler- and color-coded duplex ultrasonography. RCTs have shown that the treatment of high-grade asymptomatic carotid stenosis with carotid endarterectomy (CEA) can lower the 5-year risk of stroke from 11% to 5%. Intensive conservative treatment may lower the stroke risk still further. Moreover, RCTs have shown that CEA for symptomatic 50% to 99% carotid stenosis lowers the 5-year stroke risk by 5% to 16%. Meta-analyses of the 13 available RCTs comparing carotid artery stenting (CAS) with CEA have shown that CAS is associated with a 2% to 2.5% higher risk of periprocedural stroke or death and with a 0.5% to 1% lower risk of periprocedural myocardial infarction. If no particular surgical risk factors are present, CEA is the standard treatment for high-grade carotid stenosis. CAS may be considered as an alternative to CEA if the rate of procedure-related stroke or death can be kept below 3% or 6% for asymptomatic and symptomatic stenosis, respectively.
conclusionFurther studies are needed so that better selection criteria can be developed for individually tailored treatment.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.