ArticleFrontiers in human neuroscience2013
Traumatic brain injury, neuroimaging, and neurodegeneration.
Article in Frontiers in human neuroscience, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 101 papers, 5 of them syntheses that pooled it.
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Who cites it
101 citing papers in PubMed, 5 syntheses or guidelines pooled it, 203 citations in OpenAlex.
- Neuroimaging Correlates of Post-Traumatic Stress Disorder in Traumatic Brain Injury: A Systematic Review of the Literature.Journal of neurotrauma · 2023Pooled it
- Challenges and opportunities for neuroimaging in young patients with traumatic brain injury: a coordinated effort towards advancing discovery from the ENIGMA pediatric moderate/severe TBI group.Brain imaging and behavior · 2021Pooled it
- The Effects of Moderate-to-Severe Traumatic Brain Injury on Episodic Memory: a Meta-Analysis.Neuropsychology review · 2019Pooled it
- A systematic review of cross-sectional differences and longitudinal changes to the morphometry of the brain following paediatric traumatic brain injury.NeuroImage. Clinical · 2019Pooled it
- Behavioral and Emotional Dyscontrol Following Traumatic Brain Injury: A Systematic Review of Neuroimaging and Electrophysiological Correlates.Journal of the Academy of Consultation-Liaison PsychiatryPooled it
- Regional brain volume prior to treatment is linked to outcome after cognitive rehabilitation in traumatic brain injury.NeuroImage. Clinical · 2022Trial
- Brain Magnetic Resonance Imaging Volumetric Measures of Functional Outcome after Severe Traumatic Brain Injury in Adolescents.Journal of neurotrauma · 2021Trial
- Younger Age of First Exposure to American Football Is Associated with Worse Informant-Reported Clinical Outcomes in Older Age Brain Donors.Journal of neurotrauma · 2026Article
- Transdiagnostic MRI-derived Features of Psychopathology Following Traumatic Brain Injury: A Systematic Review.Neuropsychology review · 2026Review
- Resting State Networks and Their Associations with Cognitive Functions in Traumatic Brain Injury: An Integrative Review.Annals of neurosciences · 2026Review
- Elovanoid neuroprotection targets cell transcriptomics and proteomics to sustain synaptic integrity after brain injury.Communications biology · 2026Article
- Contusions bias cortical thickness estimates after traumatic brain injury: A TRACK-TBI study.NeuroImage. Clinical · 2026Article
- Synaptic Pathology in Traumatic Brain Injury and Therapeutic Insights.International journal of molecular sciences · 2025Review
- White Matter Integrity in Women with Repetitive Traumatic Brain Injury due to Intimate Partner Violence.Journal of neurotrauma · 2025Article
- Disrupted flexible use of context-dependent relational memory in adults following moderate-severe traumatic brain injury.Neuropsychologia · 2025Article
- Dynamic visualization of brain pulsations using amplified MRI: methodology and applications.Interface focus · 2025Article
- Anatomic Interpretability in Neuroimage Deep Learning: Saliency Approaches for Typical Aging and Traumatic Brain Injury.Neuroinformatics · 2024Article
- Evolution of Severe Closed Head Injury: Assessing Ventricular Volume and Behavioral Measures at 30 and 90 Days Post-Injury.Journal of clinical medicine · 2024Article
- Treatment effects of N-acetyl cysteine on resting-state functional MRI and cognitive performance in patients with chronic mild traumatic brain injury: a longitudinal study.Frontiers in neurology · 2024Article
- Traumatic brain injuries: a neuropsychological review.Frontiers in behavioral neuroscience · 2024Review
41 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Depending on severity, traumatic brain injury (TBI) induces immediate neuropathological effects that in the mildest form may be transient but as severity increases results in neural damage and degeneration. The first phase of neural degeneration is explainable by the primary acute and secondary neuropathological effects initiated by the injury; however, neuroimaging studies demonstrate a prolonged period of pathological changes that progressively occur even during the chronic phase. This review examines how neuroimaging may be used in TBI to understand (1) the dynamic changes that occur in brain development relevant to understanding the effects of TBI and how these relate to developmental stage when the brain is injured, (2) how TBI interferes with age-typical brain development and the effects of aging thereafter, and (3) how TBI results in greater frontotemporolimbic damage, results in cerebral atrophy, and is more disruptive to white matter neural connectivity. Neuroimaging quantification in TBI demonstrates degenerative effects from brain injury over time. An adverse synergistic influence of TBI with aging may predispose the brain injured individual for the development of neuropsychiatric and neurodegenerative disorders long after surviving the brain injury.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.