SynthesisWorld journal of gastroenterology2013
Single-incision laparoscopic appendectomy vs conventional laparoscopic appendectomy: systematic review and meta-analysis.
Synthesis in World journal of gastroenterology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 6 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 6 syntheses or guidelines pooled it.
- Single-incision versus conventional multi-incision laparoscopic appendicectomy for suspected uncomplicated appendicitis.The Cochrane database of systematic reviews · 2025Pooled it
- Single-incision versus conventional multi-incision laparoscopic appendicectomy for suspected uncomplicated appendicitis.The Cochrane database of systematic reviews · 2024Pooled it
- The use of expanding ports in laparo-endoscopic single-site surgery may cause more pain: a meta-analysis of randomized clinical trials.Surgical endoscopy · 2017Pooled it
- Interventions to optimize recovery after laparoscopic appendectomy: a scoping review.Surgical endoscopy · 2017Pooled it
- Methodological overview of systematic reviews to establish the evidence base for emergency general surgery.The British journal of surgery · 2017Pooled it
- Diagnosis and management of acute appendicitis. EAES consensus development conference 2015.Surgical endoscopy · 2016Guideline
- Evolving Paradigms in Minimal Access Surgery: A Comprehensive Review of Single-Incision Laparoscopic Appendicectomy.Cureus · 2026Review
- Impact of body mass index on perioperative outcomes and short-term recovery profiles of single-incision laparoscopic appendectomy: a propensity score-matched analysis.Frontiers in medicine · 2026Article
- Post-endoscopic retrograde appendicitis therapy stent impaction leading to exacerbation of appendicitis: A case report.World journal of clinical cases · 2025Article
- Is transumbilical laparoscopic-assisted appendectomy feasible for complicated appendicitis? A single-center experience.Pediatric surgery international · 2024Article
- Single-incision laparoscopic splenectomy in children with massive splenomegaly: A prospective, monocentric pilot study.Frontiers in pediatrics · 2022Article
- Article
- Single-Incision, Two-Port Laparoscopic Appendectomy as an Alternative to Transumbilical Single-Port Laparoscopic Appendectomy.Journal of minimally invasive surgery · 2019Article
- Bayesian network meta-analysis of the effects of single-incision laparoscopic surgery, conventional laparoscopic appendectomy and open appendectomy for the treatment of acute appendicitis.Experimental and therapeutic medicine · 2017Article
- The learning curve of single-port laparoscopic appendectomy performed by emergent operation.World journal of emergency surgery : WJES · 2016Article
- Internal hernia caused by epiploic appendices successfully treated by single-incision laparoscopic surgery (SILS).Hernia : the journal of hernias and abdominal wall surgery · 2015Article
- Short-term surgical outcomes of reduced port surgery for esophageal achalasia.Surgery today · 2015Article
- Single-Incision Robotic Colectomy (SIRC) case series: initial experience at a single center.Surgical endoscopy · 2015Article
- Is laparoscopic appendectomy going to be standard procedure for acute appendicitis; a 5-year single center experience with 1,788 patients.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2015Article
- Single port laparoscopy in gastroenterology and hepatology: a fine step forward.World journal of gastroenterology · 2014Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimTo assess the differences in clinical benefits and disadvantages of single-incision laparoscopic appendectomy (SILA) and conventional laparoscopic appendectomy (CLA).
methodsThe Cochrane Library, MEDLINE, Embase, Science Citation Index Expanded, and Chinese Biomedical Literature Database were electronically searched up through January 2013 to identify randomized controlled trails (RCTs) comparing SILA with CLA. Data was extracted from eligible studies to evaluate the pooled outcome effects for the total of 1068 patients. The meta-analysis was performed using Review Manager 5.2.0. For dichotomous data and continuous data, the risk ratio (RR) and the mean difference (MD) were calculated, respectively, with 95%CI for both. For continuous outcomes with different measurement scales in different RCTs, the standardized mean difference (SMD) was calculated with 95%CI. Sensitivity and subgroup analyses were performed when necessary.
resultsSix RCTs were identified that compared SILA (n = 535) with CLA (n = 533). Five RCTs had a high risk of bias and one RCT had a low risk of bias. SILA was associated with longer operative time (MD = 5.68, 95%CI: 3.91-7.46, P < 0.00001), higher conversion rate (RR = 5.14, 95%CI: 1.25-21.10, P = 0.03) and better cosmetic satisfaction score (MD = 0.52, 95%CI: 0.30-0.73, P < 0.00001) compared with CLA. No significant differences were found for total complications (RR = 1.15, 95%CI: 0.76-1.75, P = 0.51), drain insertion (RR = 0.72, 95%CI: 0.41-1.25, P = 0.24), or length of hospital stay (SMD = 0.04, 95%CI: -0.08-0.16, P = 0.57). Because there was not enough data among the analyzed RCTs, postoperative pain was not calculated.
conclusionThe benefit of SILA is cosmetic satisfaction, while the disadvantages of SILA are longer operative time and higher conversion rate.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.