ReviewWorld journal of gastroenterology2013
Portal hypertension and gastrointestinal bleeding: diagnosis, prevention and management.
Review in World journal of gastroenterology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers, 4 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
41 citing papers in PubMed, 4 syntheses or guidelines pooled it, 98 citations in OpenAlex.
- Anorectal emergencies: WSES-AAST guidelines.World journal of emergency surgery : WJES · 2021Pooled it
- Recommendations on the Diagnosis and Initial Management of Acute Variceal Bleeding and Hepatorenal Syndrome in Patients with Cirrhosis.Digestive diseases and sciences · 2019Guideline
- Pooled it
- Balloon-Occluded Retrograde Transvenous Obliteration (BRTO) for Treatment of Gastric Varices: Review and Meta-Analysis.Digestive diseases and sciences · 2015Pooled it
- Management Strategies for Refractory Esophageal Varices.DEN open · 2026Review
- Esophagogastric Variceal Bleeding in Cirrhotic Patients with Hepatocellular Carcinoma Receiving Systemic Therapy: A Retrospective Cohort Study.Journal of hepatocellular carcinoma · 2026Article
- Heart rate variability in the clinical assessment of patients with chronic liver disease.World journal of hepatology · 2025Review
- Predictive value of platelet counts to detect grade of esophageal varices in liver cirrhosis.Journal of family medicine and primary care · 2025Article
- Nomogram for predicting survival after transjugular intrahepatic portosystemic shunt in portal hypertension patients with bleeding.World journal of gastrointestinal surgery · 2025Article
- Effect of portal pressure gradient reduction on outcomes after transjugular intrahepatic portosystemic shunt in portal hypertension patients.World journal of hepatology · 2025Article
- A survey of emergency medicine physicians' knowledge, attitude, and practice towards esophagogastric variceal bleeding.International journal of emergency medicine · 2025Article
- Renal dysfunction contributes to deteriorated survival outcomes in patients with upper and lower gastrointestinal bleeding: insights from a cohort study of 1160 cases.Scientific reports · 2025Article
- Predicting the gastrointestinal bleeding of HBV-related acute-on-chronic liver failure based on machine learning.Frontiers in medicine · 2025Article
- Effect of diabetes on mortality and liver transplantation in alcoholic liver cirrhotic patients with acute decompensation.Hepatology international · 2024Article
- Outcomes of endoscopic sclerotherapy for jejunal varices at the site of choledochojejunostomy (with video): Three case reports.World journal of gastroenterology · 2024Article
- Review
- Serum Gastrin and Pepsinogen Levels after Administration of Acid Secretion Inhibitors for Ulcers due to Endoscopic Submucosal Dissection in Patients with Early Gastric Cancer.Gastroenterology research and practice · 2022Article
- Von Willebrand factor and esophageal varices in children with chronic liver diseases.Clinical and experimental hepatology · 2021Article
- Child-Pugh B or C Cirrhosis Increases the Risk for Bleeding Following Colonoscopic Polypectomy.Gut and liver · 2020Article
- Gastrointestinal bleeding in patients with pancreatic cancer: Causes and haemostatic treatments.United European gastroenterology journal · 2020Observational
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Bleeding from esophageal varices is a life threatening complication of portal hypertension. Primary prevention of bleeding in patients at risk for a first bleeding episode is therefore a major goal. Medical prophylaxis consists of non-selective beta-blockers like propranolol or carvedilol. Variceal endoscopic band ligation is equally effective but procedure related morbidity is a drawback of the method. Therapy of acute bleeding is based on three strategies: vasopressor drugs like terlipressin, antibiotics and endoscopic therapy. In refractory bleeding, self-expandable stents offer an option for bridging to definite treatments like transjugular intrahepatic portosystemic shunt (TIPS). Treatment of bleeding from gastric varices depends on vasopressor drugs and on injection of varices with cyanoacrylate. Strategies for primary or secondary prevention are based on non-selective beta-blockers but data from large clinical trials is lacking. Therapy of refractory bleeding relies on shunt-procedures like TIPS. Bleeding from ectopic varices, portal hypertensive gastropathy and gastric antral vascular ectasia-syndrome is less common. Possible medical and endoscopic treatment options are discussed.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.