Evidence map›Paper›PMID 23962513›Full record

ArticleJournal of the National Cancer Institute. Monographs2013

The challenge of conducting comparative effectiveness research in cancer: the impact of a fragmented U.S. health-care system.

Paul A Fishman, Mark C Hornbrook, Debra P Ritzwoller, Maureen C O'Keeffe-Rosetti, Jennifer Elston Lafata, Ramzi G Salloum

Open access · bronzeAbstract read
In one paragraph

Article in Journal of the National Cancer Institute. Monographs, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
6.9field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Comparing cancer care, outcomes, and costs across health systems: charting the course.Journal of the National Cancer Institute. Monographs · 2013
    Article
  6. Economic studies in colorectal cancer: challenges in measuring and comparing costs.Journal of the National Cancer Institute. Monographs · 2013
    Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

Paul A FishmanGroup Health Research Institute, 1730 Minor Ave, Suite 1600, Seattle, WA 98101, USA. fishman.p@ghc.org
Mark C Hornbrook
Debra P Ritzwoller
Maureen C O'Keeffe-Rosetti
Jennifer Elston Lafata
Ramzi G Salloum
Henry Ford Health System · USKaiser Permanente Washington Health Research Institute · USKaiser Permanente · USVirginia Commonwealth University · US

Funding

The HMO Cancer Research Network (CRN)U19CA079689 · NCI · KAISER FOUNDATION HEALTH PLAN OF WASHINGTON · PI WAGNER, EDWARD H · 1999 to 2011
$62.6M
Cancer Training GrantR25CA116339 · NCI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI BASCH, ETHAN M., REEVE, BRYCE B · 2008 to 2017
$4.0M
Medical Care Burden of Cancer: System and Data IssuesR01CA114204 · NCI · KAISER FOUNDATION RESEARCH INSTITUTE · PI HORNBROOK, MARK CHRISTOPHER · 2007 to 2010
$2.7M
Building CER Capacity: Aligning CRN, CMS, and State Resources to Map Cancer CareRC2CA148185 · NCI · DANA-FARBER CANCER INST · PI RITZWOLLER, DEBRA P, WEEKS, JANE C. · 2009 to 2009
$2.0M
Comparative effectiveness in genomic & personalized medicine for colon cancerUC2CA148471 · NCI · KAISER FOUNDATION RESEARCH INSTITUTE · PI GODDARD, KATRINA A., KUSHI, LAWRENCE H · 2010 to 2010
$2.0M
NCI NIH HHS 5UC2CA148471NCI NIH HHS R01 CA 114204NCI NIH HHS R01 CA114204NCI NIH HHS R25 CA116339NCI NIH HHS RC2 CA148185NCI NIH HHS U19 CA079689NCI NIH HHS U19 CA79689NCI NIH HHS UC2 CA148471
6 · The paper itself

Abstract

Comparative effectiveness research (CER) can make important contributions to the transformation of US health care by filling gaps left by tightly controlled clinical trials. However, without comprehensive and comparable data that reflect the diversity of the US health-care system, CER's value will be diminished. We document the limits of observational CER by examining the age at diagnosis, disease stage, and select measures of health-care use among individuals diagnosed with incident cancer aged 65 or older from four large health maintenance organizations (HMOs) relative to seniors identified through the linked Surveillance, Epidemiology, and End Results (SEER)-Medicare data for the period 1999-2007. Aged individuals in the HMOs were younger, diagnosed at earlier stages, and more likely to receive care in inpatient settings than individuals in the linked SEER-Medicare data. These differences highlight the need for comprehensive and comparable datasets that reflect the diversity of US health care to support CER that can inform health-care reform in the United States.

Indexed as

Comparative Effectiveness ResearchDelivery of Health CareHealth Maintenance OrganizationsMedicareNeoplasmsAgedAged, 80 and overFemaleHumansMaleSEER ProgramUnited States

Identifiers

PMID23962513
PMCPMC3748001
OpenAlexW2162993440

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.