ArticleBMC evolutionary biology2013
Complete mitogenome sequences of four flatfishes (Pleuronectiformes) reveal a novel gene arrangement of L-strand coding genes.
Article in BMC evolutionary biology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.
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30 citing papers in PubMed, 52 citations in OpenAlex.
- Article
- Evolutionary patterns of the mitochondrial control region in vertebrates: A large-scale comparative analysis.PloS one · 2026Article
- Comprehensive analysis of 111 Pleuronectiformes mitochondrial genomes: insights into structure, conservation, variation and evolution.BMC genomics · 2025Article
- The complete mitochondrial genome ofMitochondrial DNA. Part B, Resources · 2025Article
- Complete mitogenome and intra-family comparative mitogenomics showed distinct position of Pama Croaker Otolithoides pama.Scientific reports · 2024Article
- Comparative mitochondrial genome brings insights to slight variation in gene proportion and large intergenic spacer and phylogenetic relationship of mudskipper species.Scientific reports · 2024Article
- Complete mitochondrial genome sequence and phylogenetic analysis of the hybrid flat fishMitochondrial DNA. Part B, Resources · 2024Article
- Article
- Novel mitochondrial genome rearrangements including duplications and extensive heteroplasmy could underlie temperature adaptations in Antarctic notothenioid fishes.Scientific reports · 2023Article
- Article
- Comparative Analysis of Complete Mitochondrial Genome ofBiology · 2023Article
- Comparative Mitogenomic Analysis of Two Snake Eels Reveals Irregular Gene Rearrangement and Phylogenetic Implications of Ophichthidae.Animals : an open access journal from MDPI · 2023Article
- The study on the complete mitochondrial genome ofMitochondrial DNA. Part B, Resources · 2023Article
- Characteristics and phylogenetic analysis of the complete mitochondrial genome ofMitochondrial DNA. Part B, Resources · 2023Article
- Mitogenome of Knodus borki (Cypriniformes: Characidae): genomic characterization and phylogenetic analysis.Molecular biology reports · 2022Article
- Novel mitochondrial gene rearrangements pattern in the millipedeEcology and evolution · 2022Article
- Novel Gene Rearrangement in the Mitochondrial Genome of ThreeFrontiers in genetics · 2022Article
- The Entire Mitochondrial Genome of Macrophthalmus abbreviatus Reveals Insights into the Phylogeny and Gene Rearrangements of Brachyura.Biochemical genetics · 2021Article
- Not Frozen in the Ice: Large and Dynamic Rearrangements in the Mitochondrial Genomes of the Antarctic Fish.Genome biology and evolution · 2021Article
- Quantification and evolution of mitochondrial genome rearrangement in Amphibians.BMC ecology and evolution · 2021Article
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundFew mitochondrial gene rearrangements are found in vertebrates and large-scale changes in these genomes occur even less frequently. It is difficult, therefore, to propose a mechanism to account for observed changes in mitogenome structure. Mitochondrial gene rearrangements are usually explained by the recombination model or tandem duplication and random loss model.
resultsIn this study, the complete mitochondrial genomes of four flatfishes, Crossorhombus azureus (blue flounder), Grammatobothus krempfi, Pleuronichthys cornutus, and Platichthys stellatus were determined. A striking finding is that eight genes in the C. azureus mitogenome are located in a novel position, differing from that of available vertebrate mitogenomes. Specifically, the ND6 and seven tRNA genes (the Q, A, C, Y, S1, E, P genes) encoded by the L-strand have been translocated to a position between tRNA-T and tRNA-F though the original order of the genes is maintained.
conclusionsThese special features are used to suggest a mechanism for C. azureus mitogenome rearrangement. First, a dimeric molecule was formed by two monomers linked head-to-tail, then one of the two sets of promoters lost function and the genes controlled by the disabled promoters became pseudogenes, non-coding sequences, and even were lost from the genome. This study provides a new gene-rearrangement model that accounts for the events of gene-rearrangement in a vertebrate mitogenome.
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