Evidence map›Paper›PMID 23961492›Full record

ArticleIndian journal of endocrinology and metabolism2013

Carotid intima media thickness in type 2 diabetes mellitus with ischemic stroke.

Sunil Kumar Kota, Girija Ballav Mahapatra, Siva Krishna Kota, Syed Naveed, Prabhas Rranjan Tripathy, Sruti Jammula, Kirtikumar D Modi

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PubMed Full text at PMC Publisher
In one paragraph

Article in Indian journal of endocrinology and metabolism, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 2 pooled it
2.2field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 2 syntheses or guidelines pooled it, 63 citations in OpenAlex.

  1. Pooled it
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  17. Association Between IL-18 and Carotid Intima-Media Thickness in Patients with Type II Diabetic Nephropathy.Medical science monitor : international medical journal of experimental and clinical research · 2017
    Article
  18. Association of retinopathy and intima media thickness of common carotid artery in type 2 diabetic patients.Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences · 2015
    Article
  19. Article
  20. Glycemic variability: Clinical implications.Indian journal of endocrinology and metabolism · 2013
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 2 countries.

Sunil Kumar KotaDepartment of Endocrinology, Medwin Hospitals, Hyderabad, Andhra Pradesh, India.
Girija Ballav Mahapatra
Siva Krishna Kota
Syed Naveed
Prabhas Rranjan Tripathy
Sruti Jammula
Kirtikumar D Modi
Medwin Hospital · INAll India Institute of Medical Sciences Bhubaneswar · INInstitute of Medical Sciences and Sum Hospital · INRoland Institute of Pharmaceutical Sciences · INSecurity Forces Hospital · SA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDiabetes mellitus is associated with high cardiovascular risk. Carotid intima media thickness (CIMT) is used commonly as a noninvasive test for the assessment of degree of atherosclerosis. The objective of this study was to find out the cut-off point for CIMT for ischemic stroke in patients with type 2 diabetes mellitus (T2DM) and to correlate CIMT with various parameters like smoking, hypertension, lipid profile and duration of T2DM. MATERIALS AND

methodsA total of 80 subjects in the age group of 30-75 years (M:F = 57:23) were selected and divided into three groups, i.e. diabetes with ischemic stroke, diabetes and healthy subjects. All the participants were subjected to B-mode ultrasonography of both common carotid arteries to determine CIMT, along with history taking, physical examination and routine laboratory investigations including included fasting and 2-hour postprandial blood sugar, blood urea, serum creatinine, lipid profile, glycated hemoglobin, and microalbuminuria.

resultsPatients with T2DM with or without ischemic stroke were found to have significantly higher prevalence of increased CIMT and a value greater than 0.8 mm was found to be associated with the occurrence of stroke. The mean carotid IMT of the group as a whole was 0.840 ± 0.2 mm. The mean carotid IMT was not significantly different between T2DM patients with or without ischemic stroke (1.06 ± 0.2 vs. 0.97 ± 0.26 mm, P = 0.08). However, the mean CIMT was significantly higher in diabetic subjects compared to healthy subjects (1.01 ± 0.28 mm vs. 0.73 ± 0.08, P = 0.006). Other parameters like higher age, smoking, hypertension, hyperlipidemia, low HDL cholesterol, the glycemic parameters and the duration of diabetes were independently and significantly related to CIMT.

conclusionA high CIMT is a surrogate and reliable marker of higher risk of ischemic stroke amongst type 2 diabetic patients. Our study demonstrates the utility of carotid IMT as a simple non-invasive screening test for the assessment of atherosclerosis risk/prognosis in type 2 diabetics.

Indexed as

B-mode ultrasonographycarotid intima media thicknessdiabetes mellitusischemic stroke

Identifiers

PMID23961492
PMCPMC3743376
OpenAlexW1983628006

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.