ArticleSpringerPlus2013
Characterization of leptospira isolates from animals and humans: phylogenetic analysis identifies the prevalence of intermediate species in India.
Article in SpringerPlus, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 1 of them a synthesis that pooled it.
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Who cites it
32 citing papers in PubMed, 1 synthesis or guideline pooled it, 67 citations in OpenAlex.
- Meta-analysis of Bovine Leptospirosis Prevalence in India.Archives of Razi Institute · 2025Pooled it
- Multidrug-resistant and virulence traits in genetically distinct vesicular Leptospira inhabiting farmland and sewage in Southern India.Scientific reports · 2026Article
- Comprehensive genotyping and taxonomic analysis uncovers extensive distribution of intermediate Leptospira species in Colombia.World journal of microbiology & biotechnology · 2026Article
- Molecular identification and phylogenetic characterization ofJournal of advanced veterinary and animal research · 2026Article
- Endemicity, Clinical Features, Risk Factors, and the Potential for Severe Infection inTropical medicine and infectious disease · 2025Article
- Outbreak of Intermediate Species Leptospira venezuelensis Spread by Rodents to Cows and Humans in L. interrogans-Endemic Region, Venezuela.Emerging infectious diseases · 2024Review
- Epidemiological Features of Leptospirosis and Identification ofInfectious disease reports · 2024Article
- Evolutionary insights into the emergence of virulent Leptospira spirochetes.PLoS pathogens · 2024Article
- Evolutionary insights into the emergence of virulentbioRxiv : the preprint server for biology · 2024Article
- Leptospiral uveitis- "Transition 'from epidemic to endemic form" difficulties in laboratory confirmations.Indian journal of ophthalmology · 2023Article
- Biofilm formationHeliyon · 2023Article
- Genome Sequence of a Leptospira montravelensis Strain Isolated from Donkey Urine during a Leptospirosis Outbreak in Sardinia Island, Italy.Microbiology resource announcements · 2023Article
- Prevalence of anti-leptospiral IgM and detection of pathogenic Leptospira species DNA in neonates presenting with clinical sepsis in Southwestern Uganda.European journal of medical research · 2022Article
- Role of Diagnostics in Epidemiology, Management, Surveillance, and Control of Leptospirosis.Pathogens (Basel, Switzerland) · 2022Review
- Prevalence of anti-leptospiral antibodies and frequency distribution ofVeterinary world · 2021Article
- Regional Prevalence of IntermediatePathogens (Basel, Switzerland) · 2021Article
- Article
- Insight into the Epidemiology of Leptospirosis: A Review ofAnimals : an open access journal from MDPI · 2021Review
- Predominance ofNew microbes and new infections · 2020Article
- Low Prevalence ofTropical medicine and infectious disease · 2020Article
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Authors and funding
9 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In this study, 191 culture isolates were recovered from suspected samples of animals and humans in Ellinghausen McCullough Johnson and Harris (EMJH) medium and assessed for its morphological features by dark field microscopy. Extracted DNA from individual culture was subjected to different PCR assays for identification and characterization of leptospira. Out of 99 positive leptospira cultures, 52 pathogenic leptospira isolates were characterized at species level by using partial RNA polymerase β-subunit (rpoB) gene sequences. Phylogenetic analysis of the nucleotide sequences revealed that 30, 8, and 14 isolates belong to L. borgpetersenii / L. interrogans, L. kirschneri, and Leptospira intermediate species, respectively. Based on analysis of 99 leptospira isolates, the prevalent Leptospira species were L. borgpetersenii or L. interrogans (30.30%), L. kirschneri (8%) and Leptospira intermediate species (14.14%) in animals and humans. To the best of authors knowledge, this is the first study to use rpoB gene nucleotide sequence based phylogenetic analysis to identify/detect Leptospira intermediate species (L. wolffii) in animals and humans in India. Hence, the prevalence of this species will surely emphasize the importance of consideration of Leptospira intermediate species and formulate a way for further studies especially in understanding the newly emerging Leptospira in animals and humans and to combat the problem associated with the disease conditions.
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