ArticleJournal of research in medical sciences : the official journal of Isfahan University of Medical Sciences2013
Evaluation of vasomotor reactivity in systemic lupus erythematosus patients and its comparison with the control group.
Article in Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed.
- Affected Microcirculation and Vascular Hemodynamics in Takayasu Arteritis.Frontiers in physiology · 2022Article
- The effect of Vitamin D supplementation in disease activity of systemic lupus erythematosus patients with Vitamin D deficiency: A randomized clinical trial.Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences · 2017Article
- Intracranial hemodynamic changes in primary Sjögren syndrome: a transcranial Doppler case-control study.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2015Article
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Authors and funding
6 authors.
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Abstract
backgroundNeuropsychiatric abnormalities are among the most common manifestations of systemic lupus erythematosus (SLE). They have been proposed to be associated with impaired cerebral blood flow (CBF). Cerebral vasomotor reactivity (VMR) is a hemodynamic parameter effective in the autoregulation of CBF. The aim of the present study is to determine and compare the VMR of women with stable SLE and normal women. MATERIALS AND
methodsAccording to the study criteria 60 women in each group entered the study. VMR was evaluated with Transcranial Doppler (TCD) at rest and after one minute of breath holding.
resultsThere was no significant difference in the mean of age between two groups (31.76 ± 7.50 years in the SLE group versus 32.43 ± 4.55 years in the control group, P value: 0.64). The mean duration of SLE in the case group was 5.40 ± 3.60 years. The means of the Breath-Holding Index (BHI) in the SLE and control groups were 0.842 ± 0.72% and 0.815 ± 0.26%, respectively, which was not significantly different (P value: 0.82).
conclusionThis study indicates that the VMR of women with stable SLE is not significantly different from the age- and sex-matched normal population. However, further investigations on patients with longer SLE duration and more neuropsychological abnormality rates are suggested.
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23961285PMC3743319What OpenQuestion holds
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