ArticleSaudi journal of ophthalmology : official journal of the Saudi Ophthalmological Society2012
Unilateral eyelid swelling, proptosis and diplopia as initial manifestation of acute myeloid leukemia.
Article in Saudi journal of ophthalmology : official journal of the Saudi Ophthalmological Society, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed, 19 citations in OpenAlex.
- Orbital myeloid sarcoma misdiagnosed for subperiostal hematoma: a case report.Journal of medical case reports · 2021Article
- A case of severe dry eye disease with corneal melting as presenting complaint of acute myeloid leukaemia.SAGE open medical case reports · 2021Article
- Bilateral Ocular Exophthalmia - A Case of Atypical Acute Myeloblastic Leukemia in a Child.Journal of critical care medicine (Universitatea de Medicina si Farmacie din Targu-Mures) · 2020Article
- Myeloid sarcoma of the eyelid mimicking pre-septal cellulitis in acute myeloid leukemia.International journal of ophthalmology · 2019Article
- An Unusual Cause of Epistaxis: Paranasal Sinus Myeloid Sarcoma.Case reports in hematology · 2019Article
- Orbital myeloid sarcoma in adult mimicking nasolacrimal duct obstruction: A case report.American journal of ophthalmology case reports · 2016Article
- Bilateral Proptosis in a Child: A Rare Presentation of Acute Lymphoblastic Leukemia.Journal of ophthalmic & vision researchArticle
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Authors and funding
3 authors at 1 institution in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
Myeloid sarcoma is a tumor of immature myeloid cells occurring in many extramedullary sites, orbit being one of them where the tumor may occur prior to or after the diagnosis of underlying disease. We report a case of a 17-year-old male who presented with upper eyelid swelling, proptosis and diplopia after presumed blunt trauma without any other clinical signs and symptoms. Initial imaging suggested possibility of subperiosteal hematoma. Magnetic resonance imaging studies demonstrated a solid tumor. Complete excision of the tumor and histopathologic diagnosis revealed evidence of acute myeloid leukemia (AML). There were no other sites indicating any tumoral process; however, bone marrow aspirate revealed an evidence of systemic disease. After chemotherapy and allogenic bone marrow transplant, the patient had complete remission of his disease. An episode of graft vs host reaction resulting in severe dry eyes along with skin eruptions was treated successfully by immunosuppression and topical lubrication without any visual or systemic sequela. This case emphasizes on the need for an aggressive work-up for any unusual orbital lesion in the absence of any explainable etiology. Further, AML may be suspected in the cases of orbital tumors even in the absence of systemic manifestations of leukemia at any age.
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