ArticleSaudi journal of ophthalmology : official journal of the Saudi Ophthalmological Society2011
Orbital retinoblastoma: Present status and future challenges - A review.
Article in Saudi journal of ophthalmology : official journal of the Saudi Ophthalmological Society, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed.
- Demographic and Clinical Characteristics of Retinoblastoma Cases at a Tertiary Care Center in Eastern India.Cureus · 2024Article
- Retinoblastoma in Asia.Eye (London, England) · 2019Review
- Recent advances and challenges in the management of retinoblastoma.Indian journal of ophthalmology · 2017Review
- Retinoblastoma in a pediatric oncology reference center in Southern Brazil.BMC pediatrics · 2016Article
- Extra-ocular retinoblastoma: about 12 cases followed at the Mohamed VI university hospital of Marrakech.The Pan African medical journal · 2016Article
- Management of retinoblastoma in children: current status.Paediatric drugs · 2015Review
- Current therapy and recent advances in the management of retinoblastoma.Indian journal of medical and paediatric oncology : official journal of Indian Society of Medical & Paediatric Oncology · 2012Article
- Orbital Retinoblastoma: From Palliation to Cure by Sequential Multimodal Multidisciplinary Therapy - A Case Report.Case reports in oncologyArticle
- Ophthalmic Artery Chemosurgery: A Nursing Perspective.Asia-Pacific journal of oncology nursingReview
- An Unexpected Response of Orbital Retinoblastoma to Inconsistent Systemic Chemotherapy Alone.Case reports in ophthalmologyArticle
- Retinoblastoma with and without Extraocular Tumor Extension: A Global Comparative Study of 3435 Patients.Ophthalmology scienceArticle
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Orbital retinoblastoma is a catastrophic event traditionally carrying a dismal prognosis. Although its incidence is less in the developed countries it continues to be one of the major diagnosis at presentation in the developing world. Orbital retinoblastoma encompasses a wide range of distinct clinical entities with varying tumor load. There are no standard treatment protocols as of now but the current preferred management is multimodal with a combination of initial high-dose chemotherapy, surgery, external beam radiotherapy and prolonged chemotherapy for twelve cycles. In spite of progress on all fronts including surgical, medical, diagnostic, genetic and rehabilitative with improving survival rates, however, lack of access to medical facilities, lack of education about the need for early medical attention and cultural resistance to enucleation continue to contribute to an epidemic of extra ocular disease at diagnosis in the developing world. This review introduces the various terminologies used in the spectrum of orbital retinoblastoma, discusses in details the clinical aspects and management protocols, current status and the future directions.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.