ArticleSaudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society2012
Formulation and evaluation of mefenamic acid emulgel for topical delivery.
Article in Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers.
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The trial behind it
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Who cites it
43 citing papers in PubMed, 248 citations in OpenAlex.
- Development, Characterization, and Clinical Evaluation of a 6% Nitroglycerin-Aloe Vera Transdermal Gel for Stable Angina Management.Drug design, development and therapy · 2026Trial
- Development of Nigella sativa essential oil loaded keratin/gelatin cryogel with antimicrobial and antioxidant properties for wound dressing.Scientific reports · 2026Article
- Formulation of a ModifiedACS omega · 2026Article
- Development and Evaluation of Antifungal Activity of Carbopol and Neem Seed Oil-Based Organogels.Anti-inflammatory & anti-allergy agents in medicinal chemistry · 2026Article
- Rose Bengal-Incorporated Supramolecular Gels as a Topical Platform for Localized Antimicrobial Photodynamic Therapy.International journal of molecular sciences · 2025Article
- In vivo efficacy of atorvastatin in the treatment of Tinea pedis: stepping forward into drug repositioning.The Journal of antibiotics · 2025Article
- Optimization and Formulation of an Emulgel Based on Clove Oil in Order to Evaluate Its Antibacterial and Anti-inflammatory Potential In Vitro and In Vivo for Topical Application.Applied biochemistry and biotechnology · 2025Article
- Fabrication of a sponge-like protein based hydrogel incorporating fluconazole against Candida species as a potential treatment for vulvovaginal candidiasis infection.Scientific reports · 2025Article
- Contemplating Novel W/O Emulsion Based Gel for Anti-Psoriatic Activity of Tofacitinib in Imiquimod-Induced Balb/C Mice Model.AAPS PharmSciTech · 2024Article
- Ursolic acid inhibits NF-κB signaling and attenuates MMP-9/TIMP-1 in progressive osteoarthritis: a network pharmacology-based analysis.RSC advances · 2024Article
- Formulation and evaluation of fluconazole emulgels for potential treatment of vaginal candidiasis.Heliyon · 2024Article
- Attenuated effects of topical vinpocetine in an imiquimod-induced mouse model of psoriasis.Journal of Taibah University Medical Sciences · 2024Article
- Enhancement of Curcumin's Anti-Psoriatic Efficacy via Formulation into Tea Tree Oil-Based Emulgel.Gels (Basel, Switzerland) · 2023Article
- Article
- Development of a Nanoemulgel for the Topical Application of Mupirocin.Pharmaceutics · 2023Article
- Development and Optimization of Novel Emulgel Loaded with Andrographolide-Rich Extract and Sesame Oil Using Quality by Design Approach: In Silico and In Vitro Cytotoxic Evaluation against A431 Cells.Gels (Basel, Switzerland) · 2023Article
- Review
- Emulsion-Based Gel Loaded with Ibuprofen and Its Derivatives.Gels (Basel, Switzerland) · 2023Article
- Dasatinib-Loaded Topical Nano-Emulgel for Rheumatoid Arthritis: Formulation Design and Optimization by QbD, In Vitro, Ex Vivo, and In Vivo Evaluation.Pharmaceutics · 2023Article
- Nanoemulgel: A Novel Nano Carrier as a Tool for Topical Drug Delivery.Pharmaceutics · 2023Review
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Emulgels have emerged as a promising drug delivery system for the delivery of hydrophobic drugs. The objective of the study was to prepare emulgel of mefenamic acid, a NSAID, using Carbapol 940 as a gelling agent. Mentha oil and clove oil were used as penetration enhancers. The emulsion was prepared and it was incorporated in gel base. The formulations were evaluated for rheological studies, spreading coefficient studies, bioadhesion strength, skin irritation studies, in vitro release, ex vivo release studies, anti-inflammatory activity and analgesic activity. Formulation F2 and F4 showed comparable analgesic and anti-inflammatory activity when they compared with marketed diclofenac sodium gel. So, it can be concluded that topical emulgel of mefenamic acid posses an effective anti-inflammatory and analgesic activity.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.