ArticleProceedings of the National Academy of Sciences of the United States of America2013
A physical explanation of the temperature dependence of physiological processes mediated by cilia and flagella.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed, 61 citations in OpenAlex.
- Experimental snowball earth viscosity drives the evolution of motile multicellularity.iScience · 2026Article
- Temperature dependence of the motility of the parasitic microswimmer Trypanosoma brucei.Biophysical journal · 2026Article
- Gene-to-Population Level Responses to Multiple Stressors on the Rocky Shore.Ecology and evolution · 2026Article
- Costs and benefits of phytoplankton motility.ArXiv · 2025Article
- Cilia in the brain display region-dependent oscillations of length and orientation.PLoS biology · 2025Article
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- Circadian cilia transcriptome in mouse brain across physiological and pathological states.Molecular brain · 2024Article
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- Regulation of Brain Primary Cilia Length by MCH Signaling: Evidence from Pharmacological, Genetic, Optogenetic, and Chemogenic Manipulations.Molecular neurobiology · 2022Article
- Quantification of Motility inFrontiers in microbiology · 2022Article
- A quantitative interspecies comparison of the respiratory mucociliary clearance mechanism.European biophysics journal : EBJ · 2022Article
- Large-scale analysis reveals spatiotemporal circadian patterns of cilia transcriptomes in the primate brain.Journal of neuroscience research · 2021Article
- Infrared-Emitting Multimodal Nanostructures for Controlled In Vivo Magnetic Hyperthermia.Advanced materials (Deerfield Beach, Fla.) · 2021Article
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- Microrheology reveals microscale viscosity gradients in planktonic systems.Proceedings of the National Academy of Sciences of the United States of America · 2021Article
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- Temporal proteomic profiling reveals insight into critical developmental processes and temperature-influenced physiological response differences in a bivalve mollusc.BMC genomics · 2020Article
- Adaptation of the Marine BacteriumInternational journal of molecular sciences · 2020Article
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- Active amplification in insect ears: mechanics, models and molecules.Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology · 2015Review
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Authors and funding
1 author at 1 institution in 1 country.
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Abstract
The majority of biological rates are known to exhibit temperature dependence. Here I reveal a direct link between temperature and ecologically relevant rates such as swimming speeds in Archaea, Bacteria, and Eukaryotes as well as fluid-pumping and filtration rates in many metazoans, and show that this relationship is driven by movement rates of cilia and flagella. I develop models of the temperature dependence of cilial and flagellar movement rates and evaluate these with an extensive compilation of data from the literature. The model captures the temperature dependence of viscosity and provides a mechanistic and biologically interpretable explanation for the temperature dependence of a range of ecologically relevant processes; it also reveals a clear dependence on both reaction rate-like processes and the physics of the environment. The incorporation of viscosity allows further insight into the effects of environmental temperature variation and of processes, such as disease, that affect the viscosity of blood or other body fluids.
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