ArticleInternational urology and nephrology2014
Red cell distribution width is associated with mortality in kidney transplant recipients.
Article in International urology and nephrology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.
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18 citing papers in PubMed, 1 synthesis or guideline pooled it, 44 citations in OpenAlex.
- Prognostic Value of Red Blood Cell Distribution Width in Non-Cardiovascular Critically or Acutely Patients: A Systematic Review.PloS one · 2016Pooled it
- Red blood cell distribution width is an independent predictor of mortality following amputation for diabetic foot.Scientific reports · 2025Article
- Association between red blood cell distribution width and non-valvular atrial fibrillation in hemodialysis patients: a single-center Chinese population study.Renal failure · 2022Article
- Succinate dehydrogenase inversely regulates red cell distribution width and healthy life span in chronically hypoxic mice.JCI insight · 2022Article
- Synchrony of biomarker variability indicates a critical transition: Application to mortality prediction in hemodialysis.iScience · 2022Article
- Distribution Width of Red Blood Cells and Related Factors Among Patients with End-Stage Renal Disease in Addis Ababa, Ethiopia.Journal of blood medicine · 2022Article
- Article
- Red Blood Cell Distribution Width Is Associated with Deterioration of Renal Function and Cardiovascular Morbidity and Mortality in Patients with Diabetic Kidney Disease.Life (Basel, Switzerland) · 2020Article
- Red cell distribution width and renal outcome in patients with non-dialysis-dependent chronic kidney disease.PloS one · 2018Observational
- Association between post-transplant red cell distribution width and prognosis of kidney transplant recipients.Scientific reports · 2017Article
- Red cell distribution width predicts incident dipstick albuminuria in Korean adults without chronic kidney disease.Kidney research and clinical practice · 2017Article
- Red Cell Distribution Width and Mortality in Hemodialysis Patients.American journal of kidney diseases : the official journal of the National Kidney Foundation · 2016Observational
- Clinical significance of red blood cell distribution width in the prediction of mortality in patients on peritoneal dialysis.Kidney research and clinical practice · 2016Article
- The Predictive Role of Red Cell Distribution Width in Mortality among Chronic Kidney Disease Patients.PloS one · 2016Article
- Elevated red blood cell distribution width in benign prostatic hyperplasia patients with metabolic syndrome.International journal of clinical and experimental medicine · 2015Article
- Red cell distribution width in renal transplant patients.International urology and nephrology · 2014Article
- The evaluation of red cell distribution width in chronic hemodialysis patients.International journal of nephrology · 2014Article
- Red cell distribution width is associated with long-term prognosis in patients with stable coronary artery disease.BMC cardiovascular disorders · 2013Observational
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Authors and funding
5 authors at 4 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundRed cell distribution width (RDW), a parameter routinely reported as part of the complete blood count, is associated with increased morbidity and mortality risk in different patient populations. No published data are available about the association between RDW and mortality in kidney transplant recipients.
methodsWe collected socio-demographic, clinical parameters, medical and transplant history and laboratory data at baseline in 723 prevalent kidney transplant recipients between June and October 2008 [mean age 51 ± 13 (SD) years, 56 % men, 21 % diabetics]. Associations between baseline RDW values and all-cause mortality over 3 years were examined in unadjusted and adjusted models.
resultsIncreasing RDW was associated with increased mortality in both unadjusted [(HR(1 % increase) = 1.63; 95 % CI 1.41-1.89) and (HR(>median) = 2.74; 95 % CI 1.68-4.48)] and fully adjusted models [(HR(1 % increase) = 1.60; 95 % CI 1.27-1.89) and (HR(>median) = 1.33; 95 % CI 0.76-2.35)]. In reclassification analyses, RDW improved the predictive value of all-cause mortality prediction models [the net reclassification improvement (NRI) was 0.189; p < 0.001].
conclusionsRDW, a cheap and readily available but largely neglected parameter independently, predicts mortality in prevalent kidney transplant recipients and could potentially been used in everyday risk assessment of kidney transplant recipients.
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