Evidence map›Paper›PMID 23959328›Full record

ReviewViruses2013

Viral subversion of the nuclear pore complex.

Valerie Le Sage, Andrew J Mouland

Open access · goldAbstract readReview
In one paragraph

Review in Viruses, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 51 papers.

0numbers the graph read from it
0cells of the map it votes in
51citing papers in PubMed
3.0field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

51 citing papers in PubMed, 80 citations in OpenAlex.

  1. Viral interference of nucleocytoplasmic transport.The Journal of biological chemistry · 2025
    Review
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  9. Nuclear transport proteins: structure, function, and disease relevance.Signal transduction and targeted therapy · 2023
    Review
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  15. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Valerie Le SageLady Davis Institute at the Jewish General Hospital, McGill University, Montreal, Quebec H3T 1E2, Canada. valerie.lesage@mail.mcgill.ca
Andrew J Mouland
McGill University · CA

Funding

Canadian Institutes of Health Research MOP-38111Canadian Institutes of Health Research MOP-56974
6 · The paper itself

Abstract

The nuclear pore complex (NPC) acts as a selective barrier between the nucleus and the cytoplasm and is responsible for mediating communication by regulating the transport of RNA and proteins. Numerous viral pathogens have evolved different mechanisms to hijack the NPC in order to regulate trafficking of viral proteins, genomes and even capsids into and out of the nucleus thus promoting virus replication. The present review examines the different strategies and the specific nucleoporins utilized during viral infections as a means of promoting their life cycle and inhibiting host viral defenses.

Indexed as

Virus Physiological PhenomenaVirus ReplicationCell NucleusCytoplasmHumansNuclear PoreRNA, ViralViral ProteinsRNA, ViralViral Proteins

Identifiers

PMID23959328
PMCPMC3761240
OpenAlexW2153943957

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.