ArticleActa biomaterialia2013
Adaptable poly(ethylene glycol) microspheres capable of mixed-mode degradation.
Article in Acta biomaterialia, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed, 31 citations in OpenAlex.
- Combinatorial Microgels for 3D ECM Screening and Heterogeneous Microenvironmental Culture of Primary Human Hepatic Stellate Cells.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024Article
- Microparticle Hydrogel Material Properties Emerge from Mixing-Induced Homogenization in a Poly(ethylene glycol) and Dextran Aqueous Two-Phase System.Macromolecules · 2023Article
- Microfluidic Platform for Microparticle Fabrication and Release of a Cathepsin Inhibitor.Tissue engineering. Part C, Methods · 2023Article
- Microfluidic Chip Device forLangmuir : the ACS journal of surfaces and colloids · 2021Article
- Controlling Structure with Injectable Biomaterials to Better Mimic Tissue Heterogeneity and Anisotropy.Advanced healthcare materials · 2021Review
- Integration of Hydrogel Microparticles With Three-Dimensional Liver Progenitor Cell Spheroids.Frontiers in bioengineering and biotechnology · 2020Article
- Printing Therapeutic Proteins in 3D using Nanoengineered Bioink to Control and Direct Cell Migration.Advanced healthcare materials · 2019Article
- Core-shell microparticles for protein sequestration and controlled release of a protein-laden core.Acta biomaterialia · 2017Article
- Stimuli-Responsive Polymeric Systems for Controlled Protein and Peptide Delivery: Future Implications for Ocular Delivery.Molecules (Basel, Switzerland) · 2016Review
- Differential regulation of angiogenesis using degradable VEGF-binding microspheres.Biomaterials · 2016Article
- Methods for Generating Hydrogel Particles for Protein Delivery.Annals of biomedical engineering · 2016Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
Abstract
A simple, degradable poly(ethylene glycol) (PEG) microsphere system formed from a water-in-water emulsion process is presented. Microsphere network degradation and erosion were controlled by adjusting the number of hydrolytically labile sites, by varying the PEG molecular weight, and by adjusting the emulsion conditions. Microsphere size was also controllable by adjusting the polymer formulation. Furthermore, it is demonstrated that alternative degradation and erosion mechanisms, such as proteolytic degradation, can be incorporated into PEG microspheres, resulting in mixed-mode degradation. Owing to the adaptability of this approach, it may serve as an attractive option for emerging tissue engineering, drug delivery and gene delivery applications.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.