Evidence map›Paper›PMID 23957941›Full record

ArticleJournal of orthopaedic surgery and research2013

Anterior cruciate ligament surgery in the rabbit.

Manon Bachy, Ines Sherifi, Fréderic Zadegan, David Petrover, Hervé Petite, Didier Hannouche

Abstract read
In one paragraph

Article in Journal of orthopaedic surgery and research, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Manon BachyLaboratoire de Bioingénierie et Bioimagerie Ostéo-Articulaire (B2OA) CNRS UMR 7052, Université Denis Diderot Paris VII, Paris, France.
Ines Sherifi
Fréderic Zadegan
David Petrover
Hervé Petite
Didier Hannouche

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundVarious methods regarding allograft knee replacements have been described. The animal models, which are generally used for this purpose include sheep, dogs, goats, and pigs, and accrue significant costs for study protocols. The authors herein describe an efficient and cost-effective model to study either native or tissue-engineered allografts for anterior cruciate ligament (ACL) replacement in a New Zealand rabbit model with the potential for transgenic and cell migration studies.

methodsACL reconstructions were performed in rabbits under general anesthesia. For fresh allograft implantations, two animals were operated in parallel. Each right extensor digitorum longus tendon was harvested and prepared for implantation. After excision of the ACL, tibial and femoral bone tunnels were created to implant each graft in the native ACL position.

resultsDuring a 2-year period, the authors have successfully undertaken this surgery in 61 rabbits and have not noticed any major complications attributed to this surgical technique. In addition, the authors have observed fast recovery in the animals postoperatively.

conclusionThe authors recommend this surgical procedure as an excellent model for the study of knee surgery.

Indexed as

Anterior Cruciate Ligament InjuriesAnesthesia, GeneralAnimalsAnimals, Genetically ModifiedAnterior Cruciate LigamentAnterior Cruciate Ligament ReconstructionDisease Models, AnimalMalePerioperative CareRabbitsSpecimen HandlingTendonsTomography, X-Ray Computed

Identifiers

PMID23957941
PMCPMC3765288

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.