ArticleBMC evolutionary biology2013
The sea lamprey has a primordial accessory olfactory system.
Article in BMC evolutionary biology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed, 31 citations in OpenAlex.
- Behavioral, Endocrine, and Neuronal Responses to Odors in Lampreys.Animals : an open access journal from MDPI · 2025Review
- Type 1 vomeronasal receptor expression in juvenile and adult lungfish olfactory organ.Zoological letters · 2023Article
- How the evolution of air breathing shaped hippocampal function.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2022Article
- Olfactory-induced locomotion in lampreys.Cell and tissue research · 2022Review
- A comprehensive structural, lectin and immunohistochemical characterization of the zebrafish olfactory system.Scientific reports · 2021Article
- Olfaction across the water-air interface in anuran amphibians.Cell and tissue research · 2021Review
- The evolutionary origins of the vertebrate olfactory system.Open biology · 2020Review
- The Zebrafish Amygdaloid Complex - Functional Ground Plan, Molecular Delineation, and Everted Topology.Frontiers in neuroscience · 2020Article
- Ethnozoological knowledge of traditional fishing villages about the anadromous sea lamprey (Petromyzon marinus) in the Minho river, Portugal.Journal of ethnobiology and ethnomedicine · 2019Article
- Mitral cell development in the olfactory bulb of sharks: evidences of a conserved pattern of glutamatergic neurogenesis.Brain structure & function · 2019Article
- GABAergic modulation of olfactomotor transmission in lampreys.PLoS biology · 2018Article
- Excreted Steroids in Vertebrate Social Communication.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2018Review
- Sensory Activation of Command Cells for Locomotion and Modulatory Mechanisms: Lessons from Lampreys.Frontiers in neural circuits · 2016Review
- Chemical cues and pheromones in the sea lamprey (Petromyzon marinus).Frontiers in zoology · 2015Review
- Ontogenetic shifts in brain scaling reflect behavioral changes in the life cycle of the pouched lamprey Geotria australis.Frontiers in neuroscience · 2015Article
Corrections and comments
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
Abstract
backgroundA dual olfactory system, represented by two anatomically distinct but spatially proximate chemosensory epithelia that project to separate areas of the forebrain, is known in several classes of tetrapods. Lungfish are the earliest evolving vertebrates known to have this dual system, comprising a main olfactory and a vomeronasal system (VNO). Lampreys, a group of jawless vertebrates, have a single nasal capsule containing two anatomically distinct epithelia, the main (MOE) and the accessory olfactory epithelia (AOE). We speculated that lamprey AOE projects to specific telencephalic regions as a precursor to the tetrapod vomeronasal system.
resultsTo test this hypothesis, we characterized the neural circuits and molecular profiles of the accessory olfactory epithelium in the sea lamprey (Petromyzon marinus). Neural tract-tracing revealed direct and reciprocal connections with the dorsomedial telencephalic neuropil (DTN) which in turn projects directly to the dorsal pallium and the rostral hypothalamus. High-throughput sequencing demonstrated that the main and the accessory olfactory epithelia have virtually identical profiles of expressed genes. Real time quantitative PCR confirmed expression of representatives of all 3 chemoreceptor gene families identified in the sea lamprey genome.
conclusionAnatomical and molecular evidence shows that the sea lamprey has a primordial accessory olfactory system that may serve a chemosensory function.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.