SynthesisBioMed research international2013
Probiotics as additives on therapy in allergic airway diseases: a systematic review of benefits and risks.
Synthesis in BioMed research international, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed, 1 synthesis or guideline pooled it, 31 citations in OpenAlex.
- Probiotics for children with asthma: a systematic review and meta-analysis.Frontiers in pediatrics · 2025Pooled it
- Recommending Oral Probiotics to Reduce Winter Antibiotic Prescriptions in People With Asthma: A Pragmatic Randomized Controlled Trial.Annals of family medicine · 2016Trial
- Probiotics in Children with Asthma.Children (Basel, Switzerland) · 2022Review
- Pediatric Obesity-Related Asthma: The Role of Nutrition and Nutrients in Prevention and Treatment.Nutrients · 2021Review
- Probiotics in Pediatrics. A Review and Practical Guide.Nutrients · 2021Review
- Prevention and Management with Pro-, Pre and Synbiotics in Children with Asthma and Allergic Rhinitis: A Narrative Review.Nutrients · 2021Review
- Probiotics in Medicine: A Long Debate.Frontiers in immunology · 2020Review
- Asthma - A Disease of How We Breathe: Role of Breathing Exercises and Pranayam.Indian journal of pediatrics · 2018Review
- Probiotics and Disease: A Comprehensive Summary-Part 7, Immune Disorders.Integrative medicine (Encinitas, Calif.) · 2017Review
- A multi-strain Synbiotic may reduce viral respiratory infections in asthmatic children: a randomized controlled trial.Electronic physician · 2016Article
- The changing face of asthma and its relation with microbes.Trends in microbiology · 2015Review
- Do children's upper respiratory tract infections benefit from probiotics?BMC infectious diseases · 2014Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundWe conducted a systematic review to find out the role of probiotics in treatment of allergic airway diseases.
methodsA comprehensive search of the major electronic databases was done till March 2013. Trials comparing the effect of probiotics versus placebo were included. A predefined set of outcome measures were assessed. Continuous data were expressed as standardized mean difference with 95% CI. Dichotomous data were expressed as odds ratio with 95% CI. P value < 0.05 was considered as significant.
resultsA total of 12 studies were included. Probiotic intake was associated with a significantly improved quality of life score in patients with allergic rhinitis (SMD -1.9 (95% CI -3.62, -0.19); P = 0.03), though there was a high degree of heterogeneity. No improvement in quality of life score was noted in asthmatics. Probiotic intake also improved the following parameters: longer time free from episodes of asthma and rhinitis and decrease in the number of episodes of rhinitis per year. Adverse events were not significant.
conclusionAs the current evidence was generated from few trials with high degree of heterogeneity, routine use of probiotics as an additive on therapy in subjects with allergic airway diseases cannot be recommended.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.