Evidence map›Paper›PMID 23956925›Full record

ArticleJournal of thyroid research2013

New approaches to thyroid hormones and purinergic signaling.

Gabriel Fernandes Silveira, Andréia Buffon, Alessandra Nejar Bruno

Open access · hybridAbstract read
In one paragraph

Article in Journal of thyroid research, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.3field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Purinergic signaling in thyroid disease.Purinergic signalling · 2023
    Review
  3. Effect of experimental hyperthyroidism onInternational journal of reproductive biomedicine · 2020
    Article
  4. Purinergic Signalling: Therapeutic Developments.Frontiers in pharmacology · 2017
    Review
  5. Purinergic signalling in endocrine organs.Purinergic signalling · 2014
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Gabriel Fernandes SilveiraInstituto Federal de Educação, Ciência e Tecnologia do Rio Grande do Sul, Porto Alegre (IFRS-POA), Rua Ramiro Barcelos 2777, 90.035-007 Porto Alegre, RS, Brazil.
Andréia Buffon
Alessandra Nejar Bruno
Instituto Federal de Educação, Ciência e Tecnologia do Rio Grande do Sul · BRUniversidade Federal do Rio Grande do Sul · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

It is known that thyroid hormones influence a wide variety of events at the molecular, cellular, and functional levels. Thyroid hormones (TH) play pivotal roles in growth, cell proliferation, differentiation, apoptosis, development, and metabolic homeostasis via thyroid hormone receptors (TRs) by controlling the expression of TR target genes. Most of these effects result in pathological and physiological events and are already well described in the literature. Even so, many recent studies have been devoted to bringing new information on problems in controlling the synthesis and release of these hormones and to elucidating mechanisms of the action of these hormones unconventionally. The purinergic system was recently linked to thyroid diseases, including enzymes, receptors, and enzyme products related to neurotransmitter release, nociception, behavior, and other vascular systems. Thus, throughout this text we intend to relate the relationship between the TH in physiological and pathological situations with the purinergic signaling.

Identifiers

PMID23956925
PMCPMC3730180
OpenAlexW2145751051

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.