ArticleAnnals of Indian Academy of Neurology2013
Clinical profile of psychogenic non-epileptic seizures in adults: A study of 63 cases.
Article in Annals of Indian Academy of Neurology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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8 citing papers in PubMed, 34 citations in OpenAlex.
- A scoping review of studies on dissociative and conversion disorders in India.Indian journal of psychiatry · 2025Review
- [Hospital frequency of non-epileptic psychogenic seizures in Bamako].The Pan African medical journal · 2024Article
- Clinical manifestations and cultural correlates of psychogenic nonepileptic seizure symptoms: An Indian perspective.Journal of family medicine and primary care · 2022Article
- Dissociation, Stressors, and Coping in Patients of Psychogenic Nonepileptic Seizures.Indian journal of psychological medicine · 2021Article
- Reliability of additional reported seizure manifestations to identify dissociative seizures.Epilepsy & behavior : E&B · 2021Article
- Psychosocial and Physiologic Characteristics of Patients with Non-epileptic Events: A Retrospective Study.Cureus · 2020Article
- Temporal Lobe Seizures Presenting as Abrupt Clinging Behavior in a Child.Indian journal of psychological medicineArticle
- Imaging in Psychogenic Nonepileptic Seizures: An Observational Study.Indian journal of psychological medicineArticle
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Authors and funding
6 authors at 1 institution in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
aimsTo evaluate clinical profile and short-term outcome of psychogenic non-epileptic seizures (PNES) in Indian adult population. SETTING AND
designA prospective observational study, conducted at tertiary teaching institute at New Delhi. MATERIALS AND
methodsSixty-three patients with confirmed PNES were enrolled. The diagnosis was based on witnessing the event during video-electroencephalography (Video-EEG) monitoring. A detailed clinical evaluation was done including evaluation for coexistent anxiety or depressive disorders. Patients were divided into two groups on the basis of excessive or paucity of movements during PNES attacks. Patients were followed-up to 12 months for their PNES frequency. STATISTICAL ANALYSIS: Means and standard deviations were calculated for continuous variables. Chi-square and Students t-test were used to compare categorical and continuous variables respectively.
resultsThe mean age at onset of PNES was 25.44 years; with F:M ratio of 9.5:1. Coexistent epilepsy was present in 13 (20.63%) cases. Twenty-two patients (44%) with only PNES (n = 50) had received antiepileptic drugs. Out of 63 patients of PNES 24 (38.1%) had predominant motor phenomenon, whereas 39 (61.9%) had limp attacks. The common features observed were pre-ictal headache, ictal eye closure, jaw clenching, resistant behavior, ictal weeping, ictal vocalization, and unresponsiveness during episodes. Comorbid anxiety and depressive disorders was seen in 62.3% and 90.16% patients, respectively. Short-term (6-12 months) outcome of 45 patients was good (seizure freedom in 46.66% and >50% improvement in 24.44% cases).
conclusionPNES is common, but frequently misdiagnosed and treated as epileptic seizures. A high index of suspicion is required for an early diagnosis. Proper disclosure of diagnosis and management of the psychiatric comorbidities can improve their outcome. LIMITATION: Limited sample size and change in seizures frequency as the only parameter for the assessment of the outcome are the two major limitations of our study.
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