ArticleJournal of conservative dentistry : JCD2013
Role of casein phosphopeptide amorphous calcium phosphate in remineralization of white spot lesions and inhibition of Streptococcus mutans?
Article in Journal of conservative dentistry : JCD, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Cited by 15 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed, 1 synthesis or guideline pooled it, 42 citations in OpenAlex.
- Is there a place for Tooth Mousse in the prevention and treatment of early dental caries? A systematic review.BMC oral health · 2015Pooled it
- Effects of different remineralization agents on MIH defects: a randomized clinical study.Clinical oral investigations · 2022Trial
- Enhancing Shear Bond Strength of Composite to In-Office Bleached Enamel with Biomimetic Remineralizing Agents: AnJournal of clinical and experimental dentistry · 2025Article
- Effectiveness of Self-Assembling Peptide (P11-4) in Dental Hard Tissue Conditions: A Comprehensive Review.Polymers · 2022Review
- Comparative Evaluation of Antibacterial Effect of Propolis and Aloe Vera, Xylitol, and Cpp-Acp Gels onInternational journal of dentistry · 2021Article
- Assessment of Enamel Remineralisation After Treatment with Four Different Remineralising Agents: A Scanning Electron Microscopy (SEM) Study.Journal of clinical and diagnostic research : JCDR · 2017Article
- Antimicrobial Capacity of Casein Phosphopeptide/Amorphous Calcium Phosphate and Enzymes in Glass Ionomer Cement in Dentin Carious Lesions.Acta stomatologica Croatica · 2015Article
- The effect of casein phosphopeptide-amorphous calcium phosphate paste and sodium fluoride mouthwash on the prevention of dentine erosion: An in vitro study.Journal of conservative dentistry : JCD · 2014Article
- Cut off values of laser fluorescence for different storage methods at different time intervals in comparison to frozen condition: A 1 year in vitro study.Journal of conservative dentistry : JCD · 2014Article
- Enamel remineralization assessment after treatment with three different remineralizing agents using surface microhardness: An in vitro study.Journal of conservative dentistry : JCD · 2014Article
- Optimal power settings of aluminum gallium arsenide lasers in caries inhibition - An in vitro study.Journal of conservative dentistry : JCDArticle
- The effect of two types chewing gum containing casein phosphopeptide-amorphous calcium phosphate and xylitol on salivary Streptococcus mutans.Journal of conservative dentistry : JCDArticle
- DIAGNOdent versus International Caries Detection and Assessment System in detection of incipient carious lesions: A diagnostic accuracy study.Journal of conservative dentistry : JCDArticle
- The Efficacy of Resin Infiltrant and Casein Phosphopeptide-amorphous Calcium Fluoride Phosphate in Treatment of White Spot Lesions (Comparative Study).Journal of International Society of Preventive & Community DentistryArticle
- Retraction: Role of casein phosphopeptide amorphous calcium phosphate in remineralization of white spot lesions and inhibition of Streptococcus mutans?Journal of conservative dentistry : JCDArticle
Corrections and comments
- Retraction · 2016-03-14Duplication of/in Article · False/Forged Authorship · Investigation by Journal/Publisher · Misconduct by Author ·
- Retracted
Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionTo promote the remineralization by ionic exchange mechanism instead of invasive techniques many remineralizing agents can be used.
objectiveTo evaluate the remineralization effects of casein phosphopeptide-amorphous calcium phosphate (CPP-ACP) on white spot lesions (WSLs) and its inhibitory effect on Streptococcus mutans colonization. MATERIALS AND
methodsThe study group consisted of 60 subjects exhibiting at least 1-WSL. Subjects were randomly divided into 2 groups: A test group using CPP-ACP cream (GC-Tooth Mousse, Leuven, Belgium) and a control group using only fluoride containing toothpaste for a period of 3-month. Baseline WSLs were scored using DIAGNOdent device (KaVo Germany) and the saliva samples were collected to measure S. mutans counts. After the 3-month period the WSLs were again recorded and the saliva collection was repeated.
resultDIAGNOdent measurements were increased by time (P = 0.002) in the control group and no statistically significant difference (P = 0.217) was found in the test group by the 3-month period. In both groups, the mutans counts were decreased in the 3-month experimental period.
conclusionThese clinical and laboratory results suggested that CPP-ACP containing cream had a slight remineralization effect on the WSL in the 3-month evaluation period however, longer observation is recommended to confirm whether the greater change in WSLs is maintained.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.