Evidence map›Paper›PMID 23956499›Full record

ArticleJournal of micromechanics and microengineering : structures, devices, and systems2013

A MEMS differential viscometric sensor for affinity glucose detection in continuous glucose monitoring.

Xian Huang, Siqi Li, Erin Davis, Charles Leduc, Yann Ravussin, Haogang Cai, Bing Song, Dachao Li, Domenico Accili, Rudolph Leibel and 2 more

Abstract read
In one paragraph

Article in Journal of micromechanics and microengineering : structures, devices, and systems, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
3.1field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 35 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. A hydrogel-based glucose affinity microsensor.Sensors and actuators. B, Chemical · 2016
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. A MEMS Dielectric Affinity Glucose Biosensor.Journal of microelectromechanical systems : a joint IEEE and ASME publication on microstructures, microactuators, microsensors, and microsystems · 2013
    Article
  12. A MEMS differential viscometric sensor for affinity glucose detection in continuous glucose monitoring.Journal of micromechanics and microengineering : structures, devices, and systems · 2013
    Article
  13. Article
  14. Article
  15. Article
  16. Cell culture on MEMS platforms: a review.International journal of molecular sciences · 2009
    Review
  17. Article
  18. Article
  19. BioMEMS -Advancing the Frontiers of Medicine.Sensors (Basel, Switzerland) · 2008
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 2 countries.

Xian HuangDepartment of Mechanical Engineering, Columbia University, New York, NY 10027.
Siqi Li
Erin Davis
Charles Leduc
Yann Ravussin
Haogang Cai
Bing Song
Dachao Li
Domenico Accili
Rudolph Leibel
Qian Wang
Qiao Lin
Columbia University · USColumbia University Irving Medical Center · USUniversity of South Carolina · USTianjin University · CN

Funding

Translational Biomarker Analytical Core (TBAC)P30DK063608 · NIDDK · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI DOMENICO ACCILI · 2003 to 2026
$36.7M
RESEARCH TRAININGP30DK026687 · NIDDK · ST. LUKE'S-ROOSEVELT INST FOR HLTH SCIS · PI Anthony W Ferrante, DYMPNA GALLAGHER · 1986 to 2026
$33.0M
MECHANISMS OF BETA CELL FAILURER01DK064819 · NIDDK · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI ACCILI, DOMENICO · 2003 to 2025
$10.5M
NIDDK NIH HHS P30 DK026687NIDDK NIH HHS P30 DK063608NIDDK NIH HHS R01 DK064819
6 · The paper itself

Abstract

Micromachined viscometric affinity glucose sensors have been previously demonstrated using vibrational cantilever and diaphragm. These devices featured a single glucose detection module that determines glucose concentrations through viscosity changes of glucose-sensitive polymer solutions. However, fluctuations in temperature and other environmental parameters might potentially affect the stability and reliability of these devices, creating complexity in their applications in subcutaneously implanted continuous glucose monitoring (CGM). To address these issues, we present a MEMS differential sensor that can effectively reject environmental disturbances while allowing accurate glucose detection. The sensor consists of two magnetically driven vibrating diaphragms situated inside microchambers filled with a boronic-acid based glucose-sensing solution and a reference solution insensitive to glucose. Glucose concentrations can be accurately determined by characteristics of the diaphragm vibration through differential capacitive detection. Our

Indexed as

affinity detectiondifferential measurementViscometric glucose sensor

Identifiers

PMID23956499
PMCPMC3743269
OpenAlexW2140575529

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.