ArticleDNA research : an international journal for rapid publication of reports on genes and genomes2013
A whole-genome analysis of a transgenic rice seed-based edible vaccine against cedar pollen allergy.
Article in DNA research : an international journal for rapid publication of reports on genes and genomes, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
22 citing papers in PubMed.
- Total RNA Extraction from Starchy Rice Endosperm.Methods in molecular biology (Clifton, N.J.) · 2025Article
- Review of the technology used for structural characterization of the GMO genome using NGS data.Genomics & informatics · 2024Article
- Whole-genome sequence analysis of mutations in rice plants regenerated from zygotes, mature embryos, and immature embryos.Breeding science · 2023Article
- SunUp and Sunset genomes revealed impact of particle bombardment mediated transformation and domestication history in papaya.Nature genetics · 2022Article
- Influence of transgenesis on genome variability in cucumber lines with aPhysiology and molecular biology of plants : an international journal of functional plant biology · 2021Article
- Identification and Validation of Genetic Variations in Transgenic Chinese Cabbage Plants (Genes · 2021Article
- Comparative whole-genome and proteomics analyses of the next seed bank and the original master seed bank of MucoRice-CTB 51A line, a rice-based oral cholera vaccine.BMC genomics · 2021Article
- Genomic variation between PRSV resistant transgenic SunUp and its progenitor cultivar Sunset.BMC genomics · 2020Article
- Analyses of transgenic fibroblast growth factor 21 mature rice seeds.Breeding science · 2019Article
- NGS sequencing reveals that many of the genetic variations in transgenic rice plants match the variations found in natural rice population.Genes & genomics · 2019Article
- The importance of genotype identity, genetic heterogeneity, and bioinformatic handling for properly assessing genomic variation in transgenic plants.BMC biotechnology · 2018Article
- Comparative analysis of miRNA expression profiles in transgenic and non-transgenic rice using miRNA-Seq.Scientific reports · 2018Article
- A bioinformatics approach for identifying transgene insertion sites using whole genome sequencing data.BMC biotechnology · 2017Article
- Re-sequencing transgenic plants revealed rearrangements at T-DNA inserts, and integration of a short T-DNA fragment, but no increase of small mutations elsewhere.Plant cell reports · 2017Article
- Biomanufacturing of protective antibodies and other therapeutics in edible plant tissues for oral applications.Plant biotechnology journal · 2016Review
- Application of whole genome shotgun sequencing for detection and characterization of genetically modified organisms and derived products.Analytical and bioanalytical chemistry · 2016Review
- Genomic variation and DNA repair associated with soybean transgenesis: a comparison to cultivars and mutagenized plants.BMC biotechnology · 2016Article
- The increasing value of plant-made proteins.Current opinion in biotechnology · 2015Review
- Comparative whole-genome analyses of selection marker-free rice-based cholera toxin B-subunit vaccine lines and wild-type lines.BMC genomics · 2015Article
- Whole-genome analysis of herbicide-tolerant mutant rice generated by Agrobacterium-mediated gene targeting.Plant & cell physiology · 2015Article
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Genetic modification (GM) by Agrobacterium-mediated transformation is a robust and widely employed method to confer new traits to crops. In this process, a transfer DNA is delivered into the host genome, but it is still unclear how the host genome is altered by this event at single-base resolution. To decipher genomic discrepancy between GM crops and their host, we conducted whole-genome sequencing of a transgenic rice line OSCR11. This rice line expresses a seed-based edible vaccine containing two major pollen allergens, Cry j 1 and Cry j 2, against Japanese cedar pollinosis. We revealed that genetic differences between OSCR11 and its host a123 were significantly less than those between a123 and its precedent cultivar Koshihikari. The pattern of nucleotide base substitution in OSCR11, relative to a123, was consistent with somaclonal variation. Mutations in OSCR11 probably occurred during the cell culture steps. In addition, strand-specific mRNA-Seq revealed similar transcriptomes of a123 and OSCR11, supporting genomic integrity between them.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.