Evidence map›Paper›PMID 23956158›Full record

ArticleAngewandte Chemie (International ed. in English)2013

β₂-adrenergic receptor activation by agonists studied with ¹⁹F NMR spectroscopy.

Reto Horst, Jeffrey J Liu, Raymond C Stevens, Kurt Wüthrich

Abstract read
In one paragraph

Article in Angewandte Chemie (International ed. in English), 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers.

0numbers the graph read from it
0cells of the map it votes in
42citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

42 citing papers in PubMed.

  1. An Excelled Trifluorinated Probe for GPCR Conformational Quantification.bioRxiv : the preprint server for biology · 2026
    Article
  2. An Improved Cysteine-Based Labeling Strategy for GPCR Structural Dynamics Studies.Chemistry (Weinheim an der Bergstrasse, Germany) · 2026
    Article
  3. Hydrogen Bonding within DynamicJournal of the American Chemical Society · 2026
    Article
  4. Review
  5. Membrane mimetic-dependence of GPCR energy landscapes.Structure (London, England : 1993) · 2024
    Article
  6. Article
  7. Single-molecule visualization of human ACommunications biology · 2023
    Article
  8. Membrane Mimetic-Dependence of GPCR Energy Landscapes.bioRxiv : the preprint server for biology · 2023
    Article
  9. Article
  10. GPCR structural characterization by NMR spectroscopy in solution.Acta biochimica et biophysica Sinica · 2022
    Review
  11. Review
  12. Slow conformational dynamics of the human AStructure (London, England : 1993) · 2022
    Article
  13. Article
  14. Review
  15. Article
  16. Article
  17. Review
  18. Capturing Peptide-GPCR Interactions and Their Dynamics.Molecules (Basel, Switzerland) · 2020
    Review
  19. Probing the YMolecules (Basel, Switzerland) · 2020
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Reto HorstDepartment of Integrative Structural and Computational Biology, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037 (USA); Present address: Pfizer Worldwide Research and Development, Eastern Point Road, Groton, CT 06340 (USA).
Jeffrey J Liu
Raymond C Stevens
Kurt Wüthrich

Funding

Structure Determination Core at SSRLU54GM094586 · NIGMS · SCRIPPS RESEARCH INSTITUTE, THE · PI WILSON, IAN A · 2010 to 2014
$40.1M
JCSG Center:Innovative Membrane Protein Technology (RMI)P50GM073197 · NIGMS · SCRIPPS RESEARCH INSTITUTE, THE · PI STEVENS, RAYMOND C · 2004 to 2013
$26.8M
Project 3U54GM094618 · NIGMS · UNIVERSITY OF SOUTHERN CALIFORNIA · PI STEVENS, RAYMOND C · 2010 to 2014
$17.1M
NIGMS NIH HHS P50 GM073197NIGMS NIH HHS U54 GM094586NIGMS NIH HHS U54 GM094618
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Adrenergic beta-2 Receptor AgonistsFluorine RadioisotopesHumansNuclear Magnetic Resonance, BiomolecularReceptors, Adrenergic, beta-2ThermodynamicsAdrenergic beta-2 Receptor AgonistsFluorine RadioisotopesReceptors, Adrenergic, beta-219F NMR spectroscopyG-protein-coupled receptorsprotein structuresβ2-adrenergic receptor

Identifiers

PMID23956158
PMCPMC3925757

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.