ArticleMedical molecular morphology2014
A rare malignancy of the parotid gland in a 13-year-old Taiwanese boy: case report of a mammary analogue secretory carcinoma of the salivary gland with molecular study.
Article in Medical molecular morphology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed, 43 citations in OpenAlex.
- Clinicopathologic features and integrated outcome analysis of pediatric and young adult salivary secretory carcinoma.Frontiers in oncology · 2026Article
- Case Report: A rare pediatric case of secretory carcinoma of the parotid gland with high-grade components misdiagnosed as pleomorphic adenoma.Frontiers in oncology · 2026Article
- Salivary Gland Secretory Carcinoma in the Facial Region: A Pediatric Case Presentation.Cureus · 2025Article
- Non Indigenous Mammary Secretory Carcinoma of Parotid Gland - An Unusual Presentation.Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India · 2024Article
- Clinicopathologic and Molecular Characterization of Four Cases of Pediatric Salivary Secretory Carcinoma (SSC), One with ETV6-RET Fusion.Head and neck pathology · 2021Article
- (Mammary Analogue) Secretory Carcinoma of the Nasal Cavity: Report of a Rare Case with p63 and DOG1 Expression and Uncommon Exon 4-Exon 14 ETV6-NTRK3 Fusion Diagnosed with Next Generation Sequencing.Head and neck pathology · 2020Article
- Mammary Analogue Secretory Carcinoma of the Palate: Case Report and Review of the Literature.Case reports in dentistry · 2019Article
- Mammary Analogue Secretory Carcinoma Arising in the Parotid Gland of Child.Plastic and reconstructive surgery. Global open · 2018Article
- Secretory carcinoma: the eastern Canadian experience and literature review.Journal of otolaryngology - head & neck surgery = Le Journal d'oto-rhino-laryngologie et de chirurgie cervico-faciale · 2018Review
- Mammary analogue secretory carcinoma of salivary glands: diagnostic pitfall with distinct immunohistochemical profile and molecular features.Rare tumors · 2017Article
- Mammary analog secretory carcinoma, low-grade salivary duct carcinoma, and mimickers: a comparative study.Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc · 2015Article
- Cytological features of mammary analogue secretory carcinoma of the parotid gland in a 15-year-old girl: a case report with review of the literature.Case reports in pathology · 2015Article
- Salivary gland tumor "wishes" to add to the next WHO Tumor Classification: sclerosing polycystic adenosis, mammary analogue secretory carcinoma, cribriform adenocarcinoma of the tongue and other sites, and mucinous variant of myoepithelioma.Head and neck pathology · 2014Article
- A Pediatric Case of High-Grade Secretory Carcinoma of the Maxillary Sinus WithPediatric and developmental pathology : the official journal of the Society for Pediatric Pathology and the Paediatric Pathology SocietyReview
- Secretory carcinoma of salivary gland - A systematic review of pediatric case reports and case series.Journal of oral and maxillofacial pathology : JOMFPReview
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Mammary analogue secretory carcinoma (MASC) is a recently described malignancy of the salivary glands characterized by an ETV6-NTRK3 (EN) fusion gene. Morphologically, MASC is sometimes difficult to distinguish from acinic cell carcinoma. Consequently, identifying the chromosomal translocation is essential for diagnosis. We present a case of parotid gland MASC in a 13-year-old boy. To the best of our knowledge, this is the youngest case reported in the literature. Histologic evaluation showed a tumor composed of microcysts, tubular structures, solid nests, or papillary architecture, with secretions within the lumens of the cysts or tubules. Immunohistochemically, tumor cells showed diffuse positive staining of S-100 protein, cytokeratin 19, and vimentin. ETV6 rearrangement was detected by fluorescence in situ hybridization and EN fusion transcripts were verified by reverse transcription (RT-PCR) assay.
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