ReviewNeurosurgical review2014
Schmorl's nodes: current pathophysiological, diagnostic, and therapeutic paradigms.
Review in Neurosurgical review, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
25 citing papers in PubMed, 74 citations in OpenAlex.
- Article
- Subtype analysis of Schmorl's nodes in the lumbar spine and the association with lumbar degeneration: a retrospective evaluation of 2262 abdominal CT scans.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2025Article
- Utilization of Bone-Anchored Annular Defect Closure to Prevent Reherniation Following Lumbar Discectomy: Overcoming Barriers to Clinical Adoption and Market Access.International journal of spine surgery · 2024Article
- Musculoskeletal Pitfalls on Molecular Imaging Studies of Oncologic Patients: How to Stay Out of Trouble.Tomography (Ann Arbor, Mich.) · 2024Review
- Schmorl's Node Found with Acute Lower Back Pain.Internal medicine (Tokyo, Japan) · 2024Article
- INTERVERTEBRAL DISC DEGENERATION INSTIGATES VERTEBRAL ENDPLATE REMODELING AND FACET JOINT PATHOLOGY IN A LARGE ANIMAL MODEL.European cells & materials · 2024Article
- IncreasedSkeletal radiology · 2023Article
- Management of low back pain accompanying sagittal plane pathologies in children: Spondylolysis/spondylolisthesis and Scheuermann's disease.Journal of children's orthopaedics · 2023Review
- Percutaneous Vertebroplasty in a Patient with Chronic Back Pain Caused by Multiple Schmorl's Nodes: A Case Report.Medicina (Kaunas, Lithuania) · 2023Article
- The Influence of Schmorl Nodes in Spinal Sagittal Balance in Young Adults.Revista brasileira de ortopedia · 2022Article
- The prevalence of Schmorl's nodes in osteoporotic vs normal patients: a Middle Eastern population study.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2022Observational
- Regenerating and repairing degenerative intervertebral discs by regulating the micro/nano environment of degenerative bony endplates based on low-tension mechanics.BMC musculoskeletal disorders · 2022Article
- Provider-patient communication: an illustrative case report of how provider language can influence patient prognosis.The Journal of the Canadian Chiropractic Association · 2022Article
- Schmorl's Node: An Uncommon Case of Back Pain and Radiculopathy.Orthopedic reviews · 2022Article
- Article
- Percutaneous vertebroplasty (PVP) to treat specialized type of endplate fractures around the Schmorl's node: a prospective study of 65 patients.Journal of orthopaedic surgery and research · 2020Article
- Schmorl Node-A Cause of Acute Thoracic Pain: A Case Report and Pathophysiological Mechanism.International journal of spine surgery · 2020Article
- Vertebral intraosseous plasma rich in growth factor (PRGF-Endoret) infiltrations as a novel strategy for the treatment of degenerative lesions of endplate in lumbar pathology: description of technique and case presentation.Journal of orthopaedic surgery and research · 2020Article
- Symptomatic Schmorl's nodes: role of percutaneous vertebroplasty. Open study on 52 patients.Neuroradiology · 2019Article
- Treatment of Naturally Degenerated Canine Lumbosacral Intervertebral Discs with Autologous Mesenchymal Stromal Cells and Collagen Microcarriers: A Prospective Clinical Study.Cell transplantation · 2019Article
Corrections and comments
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Authors and funding
2 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Schmorl's nodes were first described by the pathologist Christian Schmorl in 1927 as a herniation of the nucleus pulposus through the cartilaginous and bony endplate into the vertebral body. Although such lesions present most commonly as incidental findings in asymptomatic patients (or in patients with back or radicular pain due to other etiology), there have been several reports emphasizing the deleterious effects of the inflammatory response and endplate changes elicited by the herniation of for such reasons, Schmorl's nodes have been occasionally implicated in the etiology of chronic axial pain as well as in pathological osteoporotic fractures. In this article, a thorough literature review about the most relevant historical studies on Schmorl's nodes previously published is performed. Furthermore, the authors provide an overview about the recent advances in basic science research on the pathophysiology of such lesions, as well as on current diagnostic and therapeutic paradigms.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.