ArticleMethods (San Diego, Calif.)2014
Cow's milk allergy: from allergens to new forms of diagnosis, therapy and prevention.
Article in Methods (San Diego, Calif.), 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 69 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
69 citing papers in PubMed, 1 synthesis or guideline pooled it, 246 citations in OpenAlex.
- Specific IgE and skin prick tests to diagnose allergy to fresh and baked cow's milk according to age: a systematic review.Italian journal of pediatrics · 2017Pooled it
- Tolerance Induction in Cow's Milk Allergic Children by Heated Cow's Milk Protein: The iAGE Follow-Up Study.Nutrients · 2023Trial
- Efficacy of a Toothpaste Based on Microcrystalline Hydroxyapatite on Children with Hypersensitivity Caused by MIH: A Randomised Controlled Trial.Oral health & preventive dentistry · 2021Trial
- Iodine Fortification of a Fermented Dairy Product: Development and Quality Assessment.Foods (Basel, Switzerland) · 2026Article
- Comprehensive allergen screening and semi-quantification in plant based Milk alternatives by mass spectrometry.Food chemistry: X · 2026Article
- Production of gene-edited cloned cattle embryos using the CRISPR/EOCas12i system.Frontiers in genome editing · 2026Article
- Concordance between crude extract and component allergens in a multiple allergen simultaneous test: a large-scale retrospective analysis.British journal of biomedical science · 2026Article
- Review
- Clinical, laboratory, and therapeutic differences between immunoglobulin E-mediated and non-immunoglobulin E-mediated cow's milk protein allergy in children.World journal of clinical pediatrics · 2025Article
- Unraveling the Biological Properties of Whey Peptides and Their Role as Emerging Therapeutics in Immune Tolerance.Nutrients · 2025Review
- The importance of molecular studies in the diagnosis and monitoring of IgE-mediated cow's milk protein allergy in children: a pilot study.Postepy dermatologii i alergologii · 2025Article
- Bovine Colostrum in Pediatric Nutrition and Health.Nutrients · 2024Review
- Aptamer-based sensitive fluorescence β-lactoglobulin food allergen bioassay via dual and cyclic bidirectional strand displacement amplifications.Analytical and bioanalytical chemistry · 2024Article
- In Vitro Digestibility Assessment of Whey from Goat and Camel Milk Fermented withFoods (Basel, Switzerland) · 2024Article
- Effect of UHT Thermal Treatment on the Secondary Structures of Milk Proteins: Insights From FTIR Analysis and Potential Allergenic Activity.International journal of food science · 2024Article
- Bioactive Dairy-Fermented Products and Phenolic Compounds: Together or Apart.Molecules (Basel, Switzerland) · 2023Review
- Prevalence and Risk Factors for IgE and IgG Cow's Milk Protein Allergies in Saudi Arabia.Cureus · 2023Article
- miR-380-3p promotes β-casein expression by targeting αS1-casein in goat mammary epithelial cells.Animal bioscience · 2023Article
- The Need for Culturally Appropriate Food Allergy Management Strategies: The Indian Milk Ladder.Nutrients · 2023Article
- Preparation of Hypoallergenic Whey Protein Hydrolysate by a Mixture of Alcalase and Prozyme and Evaluation of Its Digestibility and Immunoregulatory Properties.Food science of animal resources · 2023Article
9 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
Abstract
The first adverse reactions to cow's milk were already described 2,000 years ago. However, it was only 50 years ago that several groups started with the analysis of cow's milk allergens. Meanwhile the spectrum of allergy eliciting proteins within cow's milk is identified and several cow's milk allergens have been characterized regarding their biochemical properties, fold and IgE binding epitopes. The diagnosis of cow's milk allergy is diverse ranging from fast and cheap in vitro assays to elaborate in vivo assays. Considerable effort was spent to improve the diagnosis from an extract-based into a component resolved concept. There is still no suitable therapy available against cow's milk allergy except avoidance. Therefore research needs to focus on the development of suitable and safe immunotherapies that do not elicit severe side effect.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.