Evidence map›Paper›PMID 23953804›Full record

ReviewSeminars in nephrology2013

Endocrine and hypertensive disorders of potassium regulation: primary aldosteronism.

I David Weiner

Open access · greenAbstract readReview
In one paragraph

Review in Seminars in nephrology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.0field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 20 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
  5. HIF1α is a direct regulator of steroidogenesis in the adrenal gland.Cellular and molecular life sciences : CMLS · 2021
    Article
  6. Article
  7. Article
  8. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

I David WeinerNephrology and Hypertension Section, North Florida/South Georgia Veterans Health System, Gainesville, FL 32608, USA. david.weiner@medicine.ufl.edu
University of Florida · US

Funding

H/HCO3 transport in the collecting ductR01DK045788 · NIDDK · UNIVERSITY OF FLORIDA · PI WEINER, I. DAVID · 2000 to 2017
$4.4M
H/HCO3 transport in the collecting ductR56DK045788 · NIDDK · UNIVERSITY OF FLORIDA · PI WEINER, I. DAVID · 2008 to 2008
$205k
Molecular mechanisms of ammonia metabolismI01BX000818 · VA · VETERANS HEALTH ADMINISTRATION · PI WEINER, I. DAVID · 2011 to 2014
–
H+/HCO3- TRANSPORT BY THE COLLECTING DUCTR29DK045788 · NIDDK · UNIVERSITY OF FLORIDA · PI WEINER, I. DAVID · 1993 to 1997
–
BLRD VA I01 BX000818NIDDK NIH HHS DK-045788NIDDK NIH HHS R01 DK045788NIDDK NIH HHS R56 DK045788
6 · The paper itself

Abstract

The identification of primary aldosteronism as a common cause of resistant hypertension is a significant advance in our ability to care for patients with hypertension. Primary aldosteronism is common, and when unrecognized is associated with an increased incidence of adverse cardiovascular outcomes. Identification of primary aldosteronism is based on use of the plasma aldosterone level, plasma renin activity, and the aldosterone:renin ratio. Differentiation between unilateral and bilateral autonomous adrenal aldosterone production then guides further therapy, with use of mineralocorticoid-receptor blockers for patients with bilateral autonomous adrenal aldosterone production and laparoscopic adrenalectomy for patients with unilateral autonomous aldosterone production. In this review, we discuss in detail the pathogenesis of primary aldosteronism-induced hypertension and potassium disorders, the evaluation of the patient with suspected primary aldosteronism, and the management of primary aldosteronism, both through medications and surgery.

Indexed as

Adrenal Cortex NeoplasmsAdrenalectomyAdrenocortical AdenomaAldosteroneEplerenoneHumansHyperaldosteronismHypertensionHypokalemiaMineralocorticoid Receptor AntagonistsReninSpironolactoneAldosteroneEplerenoneMineralocorticoid Receptor AntagonistsReninSpironolactoneAldosteronealdosterone-producing adenomabilateral adrenal hyperplasiahypertensionhypokalemiarenin

Identifiers

PMID23953804
PMCPMC3748390
OpenAlexW2138964456

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.