ReviewSeminars in nephrology2013
Extracellular potassium homeostasis: insights from hypokalemic periodic paralysis.
Review in Seminars in nephrology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers.
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Who cites it
43 citing papers in PubMed.
- Steroid-induced Hypokalemic Periodic Paralysis.Annals of African medicine · 2026Article
- How Does Dietary Potassium Influence BP?Journal of the American Society of Nephrology : JASN · 2026Review
- Efficacy of Retigabine in Treating Weakness in a Mouse Model of Hypokalemic Periodic Paralysis.Muscle & nerve · 2026Article
- Prediction of Postoperative Hypokalemia in Patients with Severe Carotid Artery Stenosis undergoing Standard Carotid Endarterectomy: A Retrospective Cohort Study.Annals of geriatric medicine and research · 2026Article
- Toxicological impacts of biogenic zinc oxide nanoparticles on blue Parrotfish using multibiomarker assessment.Scientific reports · 2026Article
- Thyrotoxic Paralysis in a Hispanic Woman: An Unusual Presentation of a Neurological Emergency.Cureus · 2026Article
- Potassium supplementation and depletion during development of salt-sensitive hypertension in male and female SS rats.JCI insight · 2025Article
- Mechanisms underlying the distinct K+ dependencies of periodic paralysis.The Journal of general physiology · 2025Article
- Semaglutide reverses the chronic myopathy of hyperkalemic periodic paralysis: a case report.BMC nephrology · 2025Article
- Determination of Tissue Potassium and Sodium Concentrations in Dystrophic Skeletal Muscle Tissue Using Combined Potassium (NMR in biomedicine · 2025Article
- Intermolecular Structure Conversion-Based G4-TDF Nanostructures Functionalized μPADs for Fluorescent Determination of Potassium Ion in Serum.Biosensors · 2025Article
- Hypokalemic paralysis in an adolescent following dexamethasone and B12 injection: A case report and literature review.Heliyon · 2025Article
- Electrolyte Imbalance and Neurologic Injury.CNS & neurological disorders drug targets · 2024Review
- The potassium puzzle: exploring the intriguing connection to albuminuria.Frontiers in nutrition · 2024Article
- The Prevalence and Risk Factors of Hyperkalemia in the Outpatient Setting.International journal of nephrology · 2024Article
- Hallmarks of ageing in human skeletal muscle and implications for understanding the pathophysiology of sarcopenia in women and men.Clinical science (London, England : 1979) · 2023Article
- Sodium bicarbonate and salbutamol facilitate recovery from hyperkalemia-induced electrocardiogram abnormalities in bullfrog hearts.The Journal of veterinary medical science · 2023Article
- Steroid-induced hypokalemic periodic paralysis: a case report and literature review.BMC nephrology · 2023Review
- A mathematical model of potassium homeostasis: Effect of feedforward and feedback controls.PLoS computational biology · 2022Article
- Late-Onset Hypokalemic Periodic Paralysis in an Adult Female With Type 2 Renal Tubular Acidosis: A Case Report.Cureus · 2022Article
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3 authors.
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Abstract
Extracellular potassium makes up only about 2% of the total body's potassium store. The majority of the body potassium is distributed in the intracellular space, of which about 80% is in skeletal muscle. Movement of potassium in and out of skeletal muscle thus plays a pivotal role in extracellular potassium homeostasis. The exchange of potassium between the extracellular space and skeletal muscle is mediated by specific membrane transporters. These include potassium uptake by Na(+), K(+)-adenosine triphosphatase and release by inward-rectifier K(+) channels. These processes are regulated by circulating hormones, peptides, ions, and by physical activity of muscle as well as dietary potassium intake. Pharmaceutical agents, poisons, and disease conditions also affect the exchange and alter extracellular potassium concentration. Here, we review extracellular potassium homeostasis, focusing on factors and conditions that influence the balance of potassium movement in skeletal muscle. Recent findings that mutations of a skeletal muscle-specific inward-rectifier K(+) channel cause hypokalemic periodic paralysis provide interesting insights into the role of skeletal muscle in extracellular potassium homeostasis. These recent findings are reviewed.
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