Evidence map›Paper›PMID 23952111›Full record

ArticleNeurogastroenterology and motility2013

Comparison of rectal balloon expulsion test in seated and left lateral positions.

S Ratuapli, A E Bharucha, D Harvey, A R Zinsmeister

Open access · greenAbstract readComparative Study
In one paragraph

Article in Neurogastroenterology and motility, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
43citing papers in PubMed, 2 pooled it
4.4field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

43 citing papers in PubMed, 2 syntheses or guidelines pooled it, 87 citations in OpenAlex.

  1. Guideline
  2. Guideline
  3. Trial
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  5. Effects of Alfuzosin, an αClinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association · 2019
    Trial
  6. Trial
  7. Article
  8. Article
  9. A simple four symptom-based BEDS score to predict dyssynergic defecation in patients with chronic constipation.Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2025
    Observational
  10. Article
  11. Article
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  13. Article
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  15. Article
  16. Abdomino-anal Dyscoordination in Defecatory Disorders.Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association · 2022
    Article
  17. Article
  18. Article
  19. Diagnostic Strategy and Tools for Identifying Defecatory Disorders.Gastroenterology clinics of North America · 2022
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

S RatuapliClinical Enteric Neuroscience Translational and Epidemiological Research Program, Mayo Clinic and Mayo Foundation, Rochester, MN, USA.
A E Bharucha
D Harvey
A R Zinsmeister
Mayo Clinic in Florida · USMayo Clinic · US

Funding

Pathophysiology of Anorectal DisordersR01DK078924 · NIDDK · MAYO CLINIC ROCHESTER · PI BHARUCHA, ADIL E. · 2008 to 2023
$5.0M
NIDDK NIH HHS R01 DK078924NIDDK NIH HHS R01 DK 78924
6 · The paper itself

Abstract

backgroundDefecatory disorders can be diagnosed by rectal balloon expulsion (BE) and anorectal manometry, which are traditionally evaluated in the seated and left lateral (LL) positions, respectively. The aims of this study were to compare BE in the LL and seated positions and to compare anorectal manometric parameters to BE performed in the seated and LL positions.

methods220 women [healthy (62), chronic constipation (158)] had anorectal high-resolution manometry and BE, summarized by time required (seated position, normal ≤60 s) or external traction to facilitate expulsion (LL position, normal ≤100 g). KEY

resultsBalloon expulsion results in both positions were either concordant [normal (141) or abnormal (32)] or discordant [only LL abnormal (30), only seated abnormal (17)]. There was modest agreement [κ = 0.44 (95% CI 0.30-0.57)] between seated and LL BE. Compared with subjects with normal BE in both positions, anal pressure during simulated evacuation (SE) was higher, and the rectoanal gradient (rectal-anal pressure) during SE was more negative in the other 3 categories (i.e., abnormal LL only, abnormal seated only, and both abnormal). High anal pressure during SE (OR = 1.02, 95% CI 1.00-1.04) and high rectal sensory threshold for desire to defecate (OR = 1.01, 95% CI 1.00-1.02) were associated with increased risk of abnormal BE in both positions, whereas high rectal pressure during SE (OR = 0.96, 95% CI 0.93-0.98) was associated with lower risk. CONCLUSIONS & INFERENCES: There is modest agreement between rectal BE in LL and seated positions. In addition to abnormal seated BE, which is considered indicative of pelvic floor dysfunction, high resolution manometry findings suggest that even some patients with abnormal BE in the LL position have pelvic floor dysfunction.

Indexed as

AdultAgedAged, 80 and overConstipationDiagnostic Techniques, Digestive SystemFemaleHumansManometryMiddle AgedRectumYoung Adultanorectalballoon expulsionconstipationdefecationmanometrypelvic floor

Identifiers

PMID23952111
PMCPMC3836851
OpenAlexW2161131529

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.