Evidence map›Paper›PMID 23951029›Full record

ArticlePloS one2013

Disparities in oral cancer survival among mentally ill patients.

Ting-Shou Chang, Szu-Jen Hou, Yu-Chieh Su, Li-Fu Chen, Hsu-Chieh Ho, Moon-Sing Lee, Chun-Hsuan Lin, Pesus Chou, Ching-Chih Lee

Abstract read
In one paragraph

Article in PloS one, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. The Risk and The Course of Cancer Among People with Severe Mental Illness.Clinical practice and epidemiology in mental health : CP & EMH · 2023
    Review
  10. Article
  11. Article
  12. European white paper: oropharyngeal dysphagia in head and neck cancer.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2021
    Article
  13. Article
  14. Article
  15. Expanding Access to Cancer Clinical Trials for Patients With Mental Illness.Journal of clinical oncology : official journal of the American Society of Clinical Oncology · 2019
    Article
  16. Why are somatic diseases in bipolar disorder insufficiently treated?International journal of bipolar disorders · 2019
    Review
  17. Article
  18. The Impact of Preexisting Mental Health Disorders on the Diagnosis, Treatment, and Survival among Lung Cancer Patients in the U.S. Military Health System.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2016
    Article
  19. Observational
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Ting-Shou ChangDepartment of Otolaryngology, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan.
Szu-Jen Hou
Yu-Chieh Su
Li-Fu Chen
Hsu-Chieh Ho
Moon-Sing Lee
Chun-Hsuan Lin
Pesus Chou
Ching-Chih Lee

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMany studies have reported excess cancer mortality in patients with mental illness. However, scant studies evaluated the differences in cancer treatment and its impact on survival rates among mentally ill patients. Oral cancer is one of the ten most common cancers in the world. We investigated differences in treatment type and survival rates between oral cancer patients with mental illness and without mental illness.

methodsUsing the National Health Insurance (NHI) database, we compared the type of treatment and survival rates in 16687 oral cancer patients from 2002 to 2006. The utilization rate of surgery for oral cancer was compared between patients with mental illness and without mental illness using logistic regression. The Cox proportional hazards model was used for survival analysis.

resultsOral cancer patients with mental disorder conferred a grave prognosis, compared with patients without mental illness (hazard ratios [HR] = 1.58; 95% confidence interval [CI] = 1.30-1.93; P<0.001). After adjusting for patients' characteristics and hospital characteristics, patients with mental illness were less likely to receive surgery with or without adjuvant therapy (odds ratio [OR] = 0.47; 95% CI = 0.34-0.65; P<0.001). In multivariate analysis, oral cancer patients with mental illness carried a 1.58-times risk of death (95% CI = 1.30-1.93; P<0.001).

conclusionsOral cancer patients with mental illness were less likely to undergo surgery with or without adjuvant therapy than those without mental illness. Patients with mental illness have a poor prognosis compared to those without mental illness. To reduce disparities in physical health, public health strategies and welfare policies must continue to focus on this vulnerable group.

Indexed as

Persons with Psychiatric DisordersAdultAgedBipolar DisorderChemoradiotherapy, AdjuvantCombined Modality TherapyDatabases, FactualFemaleHealthcare DisparitiesHumansKaplan-Meier EstimateLogistic ModelsMaleMiddle AgedMouth NeoplasmsMultivariate Analysis

Identifiers

PMID23951029
PMCPMC3737269

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.